Results 241 to 250 of about 9,201,564 (391)

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease

Proceedings of the National Academy of Sciences of the United States of America, 2013
K. Sathasivam, Andreas Neueder, T. A. Gipson, C. Landles, Agnesska C. Benjamin, Marie K Bondulich, Donna L. Smith, R. Faull, R. Roos, D. Howland, P. Detloff, D. Housman, G. Bates   +12 more
semanticscholar   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source

Poly ADP-ribose signaling is dysregulated in Huntington disease. [PDF]

Proc Natl Acad Sci U S A
Maiuri T, Bazan CB, Harding RJ, Begeja N, Kam TI, Byrne LM, Rodrigues FB, Warner MM, Neuman K, Mansoor M, Badiee M, Dasovich M, Wang K, Thompson LM, Leung AKL, Andres SN, Wild EJ, Dawson TM, Dawson VL, Arrowsmith CH, Truant R.   +20 more
europepmc   +1 more source

A Phenotypic Atlas for Huntington Disease Based on Data From the Enroll-HD Cohort Study. [PDF]

Neurol Genet, 2023
Langbehn DR, Sathe SS, Loy C, Sampaio C, Mccusker EA.   +4 more
europepmc   +1 more source

Treatment of Neurogenic Voice Disorders

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This overview serves as a foundational resource for clinicians caring for neurologically complex patients presenting with voice complaints. Neurogenic voice disorders are diverse in their clinical presentations and therapeutic approaches. A thorough medical history, including family history, detailed laryngeal examination, voice assessments ...
Mausumi Syamal
wiley   +1 more source

Correction: Safety of Deutetrabenazine for the Treatment of Tardive Dyskinesia and Chorea Associated with Huntington Disease. [PDF]

Neurol Ther
Frank S, Anderson KE, Fernandez HH, Hauser RA, Claassen DO, Stamler D, Factor SA, Jimenez-Shahed J, Barkay H, Wilhelm A, Alexander JK, Chaijale N, Barash S, Savola JM, Gordon MF, Chen M.   +15 more
europepmc   +1 more source

Neuroanatomic Profile of Polyglutamine Immunoreactivity in Huntington Disease Brains [PDF]

, 2009
Emily Herndon, Christa L. Hladik, Ping Shang, Dennis K. Burns, Jack Raisanen, Charles L. White   +5 more
openalex   +1 more source

Spasmodic Dysphonia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

Home cage-based insights into motor learning and strategy adaptation in a Huntington disease mouse model. [PDF]

PLoS One
Ramandi D, Sepers MD, Wang Z, Han B, Woodard CL, Murphy TH, Raymond LA.   +6 more
europepmc   +1 more source

Dietary intake in adults at risk for Huntington disease [PDF]

, 2009
Karen Marder, Hongwei Zhao, Shirley Eberly, Caroline M. Tanner, David Oakes, Ira Shoulson   +5 more
openalex   +1 more source