Results 291 to 300 of about 9,201,564 (391)

Racial Disparities in Time to Huntington Disease Diagnosis in North America: An ENROLL-HD Analysis. [PDF]

open access: yesNeurol Clin Pract
Mendizabal A   +4 more
europepmc   +1 more source

Poster 17: Lifestyle Activity and the Age of Onset of Huntington Disease

open access: bronze, 2008
K. Trembath   +8 more
openalex   +1 more source

WONOEP XVII appraisal: Targeting network excitability beyond the synapse ‐Neurotransmitter, ionic, and electro ‐diffusions

open access: yesEpilepsia, EarlyView.
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire   +9 more
wiley   +1 more source

Investigation of four diagnostic methods to identify infectious ulcerative keratitis in horses in Colorado, USA

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Ulcerative keratitis in equine patients can result in keratomalacia and perforation. Prompt and accurate diagnostics are necessary for appropriate therapy and a favourable outcome. Objective To determine the diagnostic utility (specificity and speed) of four diagnostic methods for infectious ulcerative keratitis in the horse.
K. E. V. Jones   +5 more
wiley   +1 more source

Long-Term Health Outcomes of Huntington Disease and the Impact of Future Disease-Modifying Treatments: A Decision-Modeling Analysis. [PDF]

open access: yesNeurol Clin Pract
Guzauskas GF   +10 more
europepmc   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

open access: yesThe FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi   +16 more
wiley   +1 more source

Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]

open access: yes, 2013
Brown, Euan R.   +2 more
core   +1 more source

Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Christopher W Waters   +3 more
semanticscholar   +1 more source

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