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Continuum
This article presents a systematic approach to the diagnosis and management of choreiform disorders, focusing on Huntington disease (HD) as a model.The availability of genetic testing and imaging biomarkers has led to changes in the definition of HD, which has shifted toward pathologic instead of clinical markers.
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This article presents a systematic approach to the diagnosis and management of choreiform disorders, focusing on Huntington disease (HD) as a model.The availability of genetic testing and imaging biomarkers has led to changes in the definition of HD, which has shifted toward pathologic instead of clinical markers.
openaire +2 more sources
Therapeutic approaches to Huntington disease: from the bench to the clinic
Nature Reviews Drug Discovery, 2018Nicholas S Caron +2 more
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Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities
Nature Reviews Neurology, 2020Sarah J Tabrizi +2 more
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CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset
Cell, 2019Jong-Min Lee +2 more
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