The complete chloroplast genome of an Arctic lycophyte, Huperzia arctica (Tolm.) Sipliv. 1973 (Lycopodiaceae) [PDF]
Mitochondrial DNA. Part B. Resources, 2023 Huperzia arctica (Tolm.) Sipliv. 1973 is a lycophyte species belonging to the Lycopodiaceae family, which is widely distributed in the Arctic region of Svalbard, Norway.
Youngsim Hwang +3 more
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Combined transcriptome and widely targeted metabolome analysis reveals the potential mechanism of HupA biosynthesis and antioxidant activity in Huperzia serrata [PDF]
Frontiers in Plant ScienceIntroductionHuperzia serrata is a traditional Chinese herb that has gained much attention for its production of Huperzine A (HupA). HupA has shown promise on treating Alzheimer's disease (AD).
Hao Wu +6 more
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Antioxidant, Anti-Inflammatory, and Chemical Composition Analysis of In Vitro Huperzia serrata Thallus and Wild Huperzia serrata [PDF]
MoleculesHuperzine A is a preferred treatment option for Alzheimer’s disease. Huperzia serrata (Thunb. ex Murray) Trev. (H. serrata) has garnered significant attention for its ability to produce Huperzine A (HupA). However, natural populations of wild H. serrata (
Yongchun Huang +7 more
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Anti-neuroinflammatory effects of alkaloid-enriched extract from Huperzia serrata on lipopolysaccharide-stimulated BV-2 microglial cells [PDF]
Pharmaceutical Biology, 2023 Context Alkaloid-enriched extract of Huperzia serrata (Thunb.) Trevis (Lycopodiaceae) (HsAE) can potentially be used to manage neuronal disorders.Objective This study determines the anti-neuroinflammatory effects of HsAE on lipopolysaccharide (LPS ...
Thu Kim Dang +8 more
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The temporal and spatial endophytic fungal community of Huperzia serrata: diversity and relevance to huperzine A production by the host. [PDF]
BMC Microbiol, 2022 Background Plants maintain the steady-state balance of the mutually beneficial symbiosis relationship with their endophytic fungi through secondary metabolites.
Shen Z +8 more
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A Straightforward Procedure for the High-Yield Extraction of Tricin and Flavonoids from Ecuadorian <i>Huperzia brevifolia</i> (Lycopodiaceae). [PDF]
Plants (Basel)Rich natural sources of the flavone tricin (5,7,4′-trihydroxy-3′,5′-dimethoxyflavone; systematic IUPAC name: 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one) are actively sought since this compound is endowed with a broad spectrum ...
Armijos C +3 more
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Systematic Investigations of the Huperzine A-Producing Endophytic Fungi of <i>Huperzia serrata</i> in China and Fermentation Optimization Using OSMAC Strategy. [PDF]
MoleculesHuperzine A (HupA) can alleviate Alzheimer’s disease due to its reversible inhibition of acetylcholinesterase (AChE). The chemical synthesis and plant extraction of HupA is plagued by route complexity and resource scarcity, respectively.
Li W, Wang Z, Zhu Q, Tian P.
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High mountains of Central Europe as a refuge of surprising cytotype diversity of Huperzia selago (Lycopodiaceae) [PDF]
Alpine BotanyPolyploidization is pivotal in plant speciation, affecting adaptability, ecological tolerance and specific geographical distribution patterns. While cytotype diversity has been extensively studied in angiosperms and ferns, knowledge in homosporous ...
Kateřina Vejvodová +5 more
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Diversity of Endophytic Fungi in Huperzia serrata and Their Acetylcholinesterase Inhibitory Activity [PDF]
Sustainability, 2021 Huperzia serrata is a Huperzine A (HupA)-producing herb. HupA is a potent, reversible, highly specific, centrally active and selective acetylcholinesterase inhibitor, and is commonly used to improve Alzheimer’s disease.At present, H.
Ziyun Lu +4 more
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