Antioxidant, Anti-Inflammatory, and Chemical Composition Analysis of In Vitro Huperzia serrata Thallus and Wild Huperzia serrata [PDF]
MoleculesHuperzine A is a preferred treatment option for Alzheimer’s disease. Huperzia serrata (Thunb. ex Murray) Trev. (H. serrata) has garnered significant attention for its ability to produce Huperzine A (HupA). However, natural populations of wild H. serrata (
Yongchun Huang +7 more
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Development of polymorphic simple sequence repeat markers in Huperzia serrata (Lycopodiaceae) [PDF]
Applications in Plant Sciences, 2019 Premise The natural population size of Huperzia serrata (Lycopodiaceae) has dramatically decreased and the species has become endangered due to overexploitation. Here, we developed simple sequence repeat (SSR) markers for H.
Bin Guo +10 more
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Lycodine-Type Lycopodium Alkaloids from the Whole Plants of Huperzia serrata [PDF]
Natural Products and Bioprospecting, 2017 Three new lycodine-type Lycopodium alkaloids, namely 1-methyllycodine (1), 8α-hydroxy-15,16-dehydro-des-N-methyl-α-obscurine (2), N-methyl-16-hydroxyhuperzine B (3), and one new natural lycodine-type Lycopodium alkaloid, N-methylhuperzine A (4), along ...
Yu-Chen Liu +6 more
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In Vitro Propagation, Huperzine A Content and Antioxidant Activity of Three Genotypic Huperzia serrata [PDF]
Plants, 2021 Huperzia serrata is a traditional herb and endangered Chinese medicinal material, which has attracted much attention due to its production of Huperzine A (HupA). In vitro propagation of H.
Yan Yang +6 more
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Huperzia serrata Extract ‘NSP01’ With Neuroprotective Effects-Potential Synergies of Huperzine A and Polyphenols [PDF]
Frontiers in Pharmacology, 2021 Huperzia serrata (Thunb.) Trevis is widely used in traditional asiatic medicine to treat many central disorders including, schizophrenia, cognitive dysfunction, and dementia. The major alkaloid, Huperzine A (HA), of H. serrata is a well-known competitive
N. Callizot +6 more
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Reference gene selection for real‐time quantitative PCR assays in different tissues of Huperzia serrata based on full‐length transcriptome sequencing [PDF]
Plant Direct, 2021 Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu +5 more
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Diversity of endophytic fungal community in Huperzia serrata from different ecological areas and their correlation with Hup A content [PDF]
BMC Microbiology, 2022 Background Huperzine A (Hup A) has attracted considerable attention as an effective therapeutic candidate drug used to treat Alzheimer’s disease. Whereas, the production of Hup A from wild plants faced a major challenge, which is the wild Huperzia ...
Bo Pang +10 more
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Combined transcriptome and widely targeted metabolome analysis reveals the potential mechanism of HupA biosynthesis and antioxidant activity in Huperzia serrata [PDF]
Frontiers in Plant ScienceIntroductionHuperzia serrata is a traditional Chinese herb that has gained much attention for its production of Huperzine A (HupA). HupA has shown promise on treating Alzheimer's disease (AD).
Hao Wu +6 more
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The temporal and spatial endophytic fungal community of Huperzia serrata: diversity and relevance to huperzine A production by the host [PDF]
BMC Microbiology, 2022 Background Plants maintain the steady-state balance of the mutually beneficial symbiosis relationship with their endophytic fungi through secondary metabolites.
Zhuhui Shen +8 more
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Anti-neuroinflammatory effects of alkaloid-enriched extract from Huperzia serrata on lipopolysaccharide-stimulated BV-2 microglial cells [PDF]
Pharmaceutical Biology, 2023 Context Alkaloid-enriched extract of Huperzia serrata (Thunb.) Trevis (Lycopodiaceae) (HsAE) can potentially be used to manage neuronal disorders.Objective This study determines the anti-neuroinflammatory effects of HsAE on lipopolysaccharide (LPS ...
Thu Kim Dang +8 more
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