Results 41 to 50 of about 807 (153)

The complete chloroplast genome sequence of Huperzia javanica (sw.) C. Y. Yang in Lycopodiaceae

open access: yesMitochondrial DNA. Part B. Resources, 2017
Huperzia javanica (Sw.) C. Y. Yang is a valuable medical herb used for treating Alzheimer’s disease. Here, we described the complete chloroplast genome of H. javanica using Illumina paired-end sequencing. The total genome length is 154,415 bp, containing
Hong-rui Zhang   +3 more
doaj   +1 more source

Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease

open access: yesMolecules, 2021
Huperzine A (HupA), an alkaloid found in the club moss Huperzia serrata, has been used for centuries in Chinese folk medicine to treat dementia.
María Jesús Friedli   +1 more
doaj   +1 more source

Naumannella huperziae sp. nov., an endophytic actinobacterium isolated from Huperzia serrata (Thunb.)

open access: yesInternational Journal of Systematic and Evolutionary Microbiology, 2017
An endophytic, short rod-shaped, non-motile and non-spore-forming actinobacterium, designated strain CPCC 204135T, was isolated from a surface-sterilized medicinal plant, Huperzia serrata (Thunb.), collected from Sichuan Province, south-west China. Strain CPCC 204135T was observed to grow at temperatures between 20 and 37 °C (optimum, 28-32 °C), at pH ...
Ye, Sun   +6 more
openaire   +2 more sources

RNA-seq of aboveground sporophyte’s transcriptome of Huperzia serrata and transcriptional understanding of early steps associated with huperzine biosynthesis in forest

open access: yesCurrent Plant Biology, 2020
Chinese toothed clubmoss (Huperzia serrata) is a primitive fern native in certain types of forests. It is severely endangered in China due to its difficult propagation and massive hunting for huperzine A to improve and prevent Alzheimer’s disease.
Qing-Zhong Peng   +4 more
doaj   +1 more source

Mechanistic Insight into Binding of Huperzine A with Human Serum Albumin: Computational and Spectroscopic Approaches

open access: yesMolecules, 2022
Human serum albumin (HSA) is the most abundant protein in plasma synthesized by the liver and the main modulator of fluid distribution between body compartments.
Anas Shamsi   +7 more
doaj   +1 more source

Huperzine A - An Interesting Anticholinesterase Compound from the Chinese Herbal Medicine

open access: yesActa Medica, 1998
Huperzine A, alkaloid from the Chinese herbal medicine Qian Ceng Ta, which is prepared from the moss Huperzia serrata, has been used in China for centuries to treat fever and inflammation.
Jiří Patočka
doaj   +1 more source

Isolation and purification of Huperzine A

open access: yes浙江大学学报. 农业与生命科学版, 2002
Technique of isolation and purification of Huperzine A from Huperzia serrata (Thunb) Trev. was studied in this paper. To get rid of some pigments and other impurities, some of chemical techniques for separation such as extraction with organic acid ...
SHEN Sheng-rong   +3 more
doaj   +1 more source

Traditional Chinese medicines and Alzheimer’s disease

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2011
Traditional Chinese medicines have been widely investigated for the treatment of Alzheimer’s disease (AD) because none of the current therapies—either the cholinesterase inhibitors or antagonist of N-methyl-d-aspartate receptors—has profound effects on ...
Tzong-Yuan Wu   +2 more
doaj   +1 more source

De novo RNA sequencing and transcriptome analysis of Colletotrichum gloeosporioides ES026 reveal genes related to biosynthesis of huperzine A. [PDF]

open access: yesPLoS ONE, 2015
Huperzine A is important in the treatment of Alzheimer's disease. There are major challenges for the mass production of huperzine A from plants due to the limited number of huperzine-A-producing plants, as well as the low content of huperzine A in these ...
Guowei Zhang   +10 more
doaj   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

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