Evaluation of genetic diversity and structure of the endangered medicinal plant genus Huperzia (Lycopodiaceae) in China based on EST–SSR markers [PDF]
PhytoKeysHuperzia serrata is an endangered perennial medicinal lycophyte, primarily distributed across most regions of China, eastern and southern Asia, Oceania, and the Americas.
Muzi Li +12 more
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Diversity of Endophytic Fungi in Huperzia serrata and Their Acetylcholinesterase Inhibitory Activity [PDF]
Sustainability, 2021 Huperzia serrata is a Huperzine A (HupA)-producing herb. HupA is a potent, reversible, highly specific, centrally active and selective acetylcholinesterase inhibitor, and is commonly used to improve Alzheimer’s disease.At present, H. serrata resources have been overexploited and their artificial cultivation has lagged behind the need, so the market ...
Ziyun Lu +4 more
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Active anti-acetylcholinesterase component of secondary metabolites produced by the endophytic fungi of Huperzia serrata [PDF]
Electronic Journal of Biotechnology, 2015 Background: An endophytic fungus lives within a healthy plant during certain stages of, or throughout, its life cycle. Endophytic fungi do not always cause plant disease, and they include fungi that yield different effects, including mutual benefit, and ...
Zhejian Wang +6 more
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Molecular bioinformatics and expression analysis of the COBRA gene family in Huperzia serrata
Guangxi ZhiwuIn order to clarify the molecular bioinformatics characteristics and tissue expression patterns of the COBRA gene family members of Huperzia serrata, the physicochemical properties, domains, conserved motifs, cis-acting elements, and genes expression of ...
HUANG Yumei +3 more
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Functional Characterization and Mutagenesis Studies of a Microbial-like Diterpene Synthase from Huperzia serrata [PDF]
MoleculesOver the past decade, an increasing number of functional microbial-like terpene synthases (MTPSLs) have been reported in non-seed plants. However, whether the traditional Chinese medicinal plant H.
Ting He +5 more
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New PKS/NRPS Tenuazamines A–H from the Endophytic Fungus Alternaria alternata FL7 Isolated from Huperzia serrata [PDF]
Journal of FungiIn this paper, we present a novel class of hybrid polyketides, tenuazamines A–H (1–8), which exhibit a unique tautomeric equilibrium from Alternaria alternata FL7.
Hao Zhang +8 more
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Isolation and Characterization of Novel Huperzine-Producing Endophytic Fungi from Lycopodiaceae Species [PDF]
Journal of Fungi, 2023 Huperzine A (HupA) is an important drug for treating Alzheimer’s disease (AD) and is primarily extracted from the Huperzia serrata (Lycopodiaceae). Failures in the chemical synthesis of Hup and in vitro culture have put H. serrata in danger of extinction,
Thanh Thi Minh Le +4 more
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Diterpenoids from the Endophytic Fungus Botryosphaeria sp. P483 of the Chinese Herbal Medicine Huperzia serrata [PDF]
Molecules, 2015 Two new tetranorlabdane diterpenoids, named botryosphaerins G (1) and H (2), were isolated from the solid fermentation products of Botryosphaeria sp. P483 along with seven known tetranorlabdane diterpenes (3–9).
Yan-Mei Chen +4 more
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Huperzia crassifolia (Lycopodiaceae), a new species from China based on morphological characters and molecular evidence [PDF]
PhytoKeysA new species of the firmoss from China, Huperzia crassifolia sp. nov., is described and illustrated based on morphological characters and molecular evidence. The new species resembles species associated with the H.
Zhi-You Guo +6 more
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HorticulturaeHuperzine A (HupA) is a natural Lycopodium alkaloid known for its potent neuroprotective properties through the inhibition of acetylcholinesterase. Nevertheless, the limited understanding of its biosynthesis restricts its broader application.
Ming Lei +11 more
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