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Secondary metabolites of endophytic fungi isolated from Huperzia serrata

Fitoterapia, 2021
The natural product Huperzine A isolated from Huperzia serrata is a targeted inhibitor of acetylcholinesterase that has been approved for clinical use in the treatment of Alzheimer's disease. Given the large demand for natural sources of Huperzine A  (Hup.
Duo, Cao   +7 more
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Lycopodium alkaloids from Huperzia serrata

Fitoterapia, 2019
Five new Lycopodium alkaloids, huperzine Y1 (1), huperzine Y2 (2), huperzine Y3 (3), (+)-huperzine Z (4a) and (-)-huperzine Z (4b) as well as ten known alkaloids (5-14) were isolated from Huperzia serrata. The structures of the new compounds were established using extensive spectroscopic (1D and 2D NMR, IR, and HRESIMS) and calculated electronic ...
Fangfang, Jiang   +10 more
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Huperserratinine from Huperzia serrata

Phytochemistry, 1994
Abstract A new Lycopodium alkaloid, huperserratinine, was isolated from Huperzia serrata and its structure and NMR data were assigned unambiguously by a combination of NMR experiments and computer modelling calculations.
Da-Yuan Zhu   +4 more
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New Epoxyserratanes from Huperzia serrata

Planta Medica, 2003
Three new serratane-type epoxytriterpenoids were isolated from the whole plant of Huperzia serrata. The structures of these new compounds were characterized as 14 beta,15 beta-epoxy-3 beta-hydroxyserratan-21 beta-ol (1), 14 beta,15 beta-epoxy-3 beta-hydroxyserratan-21alpha-ol (2), and 14 beta,15 beta-epoxy-3 beta-hydroxyserratan-21alpha-ol-3 beta-O ...
Hui, Zhou   +4 more
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New Lycopodium Alkaloids from Huperzia serrata

Planta Medica, 2002
Three new lycopodium alkaloids, 11alpha-hydroxyphlegmariurine B (2), 7alpha-hydroxyphlegmariurine B (3) and 7alpha,11alpha-dihydroxyphlegmariurine B (4) along with a known compound, phlegmariurine B (1), were isolated from the herb Huperzia serrata. The structures of the above compounds were elucidated based on spectroscopic studies.
Chang-Heng, Tan   +3 more
openaire   +2 more sources

Lycopodium Alkaloids from Huperzia serrata

Helvetica Chimica Acta, 2007
AbstractThree new Lycopodium alkaloids, 2‐chlorohuperzine E (1), huperzines E′ (2), and F′ (3), along with two known compounds, huperzines E and F, were isolated from Huperzia serrata (Thunb.) Trev. Their structures were elucidated by spectroscopic methods.
Heng‐Bin Wang   +6 more
openaire   +1 more source

Lycopodiumalkaloids fromHuperzia serrata

Journal of Asian Natural Products Research, 2010
A new lycopodane-type Lycopodium alkaloid, 6α-hydroxy-5,15-oxide-lycopodane (1), and seven known alkaloids were isolated from the whole plants of Huperzia serrata. Their structures were elucidated by means of spectroscopic methods. 12-Deoxyhuperzine O (2) was reported as a naturally occurring alkaloid for the first time, and showed an antagonist effect
Yan-Fang, Yang   +6 more
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Serratane-type Triterpenoids fromHuperzia Serrata

Natural Product Research, 2004
Sixteen serratane-type triterpenoids including three new compounds, 14beta,15beta-epoxyserratan-3beta,21beta,29-triol (1), serrat-14-en-3beta,21beta,29-triol (2) and serrat-14-en-3alpha,21beta,24,29-tetraol (3), were isolated from the whole plant of Huperzia serrata (Thunb) Trev.
Hui, Zhou   +5 more
openaire   +2 more sources

Huperserines A–E, Lycopodium alkaloids from Huperzia serrata

Fitoterapia, 2014
A phytochemical study on Huperzia serrata led to the isolation of four new 5-deoxyfawcettimine-related Lycopodium alkaloids, huperserines A-D (1-4), and one new lycodine-type alkaloid, huperserine E (5). Their structures were elucidated based on spectroscopic data, including 1D and 2D NMR techniques.
Wei-Wei, Jiang   +7 more
openaire   +2 more sources

Three New Hydroxylated Serratidine Alkaloids from Huperzia Serrata

Natural Product Letters, 2002
A known compound, serratidine (1), along with three hydroxylated serratidine alkaloids, 6alpha-hydroxyserrati dine (2), 4alpha-hydroxyserratidine (3) and 4alpha,6alpha-dihydroxyserratidine (4) were isolated from the CHCl3 fraction of basic materials of whole plant of the Chinese medicinal herb Huperzia serrata.
Chang-Heng, Tan   +3 more
openaire   +2 more sources

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