Results 71 to 80 of about 9,192 (180)

Variation in huperzine A and B in Australasian Huperzia species

, 2008
Huperzine A (HupA) and huperzine B (HupB) are alkaloids with acetylcholine esterase inhibitory activity and potential applications in the treatment of Alzheimer's disease.
Whincup, Anne L., Woodrow, Ian E., Goodger, Jason Q.D., Holtum, Joseph A.M., Field, Ashley R.   +4 more
core   +1 more source

Huperzia nanlingensis (Lycopodiaceae), a new terrestrial firmoss from southern China [PDF]

, 2014
Huperzia nanlingensis sp. nov. (Lycopodiaceae) is described as a new species from southern China. The distinguishing characters, description, ecology, conservation status, detailed illustrations and photographs are provided.
Xian-chun Zhang, Qi, Xin-Ping, Xing, Fu-Wu, Nawal Shrestha, Fu-wu Xing, Yan, Yue-Hong, Zhang, Xian-Chun, Xin-ping Qi, Shrestha, Nawal, Yue-hong Yan   +9 more
core   +1 more source

Synthesis of Unnatural 2‑Substituted Quinolones and 1,3-Diketones by a Member of Type III Polyketide Synthases from Huperzia serrata

, 2016
A curcuminoids, benzalacetone-, and quinolone-producing type III polyketide synthase (HsPKS3) from Huperzia serrata uniquely catalyzes the formation of unnatural 2-substituted quinolones and 1,3-diketones via head-to-head condensation of two completely ...
Juan Wang (115708), Xiao-Hui Wang (1762348), Xiao-Ping Shi (2483098), Zhang, Le, Jun Li (6494), Zeng, Ke-Wu, Tu, Peng-Fei, Yue-Lin Song (477658), Liu, Xiao, Wang, Juan, Li, Jun, Xiao Liu (65413), Le Zhang (88249), Song, Yue-Lin, Shi, She-Po, She-Po Shi (2394322), Ke-Wu Zeng (835153), Peng-Fei Tu (545064), Shi, Xiao-Ping, Wang, Xiao-Hui   +19 more
core   +1 more source

Infraspecific Variation of Huperzine A and B in Icelandic Huperzia selago Complex [PDF]

, 2018
Publisher's version (útgefin grein)The alkaloids huperzine A and huperzine B were originally isolated from the Chinese club moss Huperzia serrata.
Olafsdottir, Elin Soffia, Sun, Hang, Deng, Tao, Omarsdottir, Sesselja, Heiðmarsson, Starri, Xu, Maonian, Wasowicz, Pawel, Thorsteinsdóttir, Margrét   +7 more
core   +2 more sources

Huperzia myriophyllifolia Holub 1985

, 2023
<p> <i>Huperzia myriophyllifolia</i> (Hayata1914:133) Holub(1985:75).</p> <p> Basionym: <i>Lycopodium serratum</i> var. <i>myriophyllifolium</i> Hayata (1914: 133).
Knapp, Ralf, Chen, De-Kui, He, Hai, Wan, Xia, Zhang, Li-Bing   +4 more
core   +1 more source

Huperzine A suppresses absence seizures in the genetic absence epilepsy rat from Strasbourg (GAERS) model of genetic generalized epilepsy with absence seizures

Epilepsia Open, Volume 9, Issue 5, Page 1826-1836, October 2024.
Abstract Objective We evaluated huperzine A treatment in the Genetic Absence Epilepsy Rat from Strasbourg (GAERS) model of genetic generalized epilepsy (GGE) with absence seizures. Methods Adult male GAERS (N = 15) were implanted with EEG recording electrodes 10 days before receiving study drug.
Pablo M. Casillas‐Espinosa, Jennie Garcia‐Olivares, Rui Li, Crystal Li, Chungping Yu, Andrea E. Formella, Terence J. O'Brien   +6 more
wiley   +1 more source

The use of Huperzia species for the treatment of Alzheimer's disease

, 2020
Alzheimer's disease (AD), which relates to nervous degeneration, is the most popular form of memory loss. The pathogenesis of AD is not fully understood, and there are no therapies for this disorder. Some drugs have been used in clinical applications for
Ngoc Huyen N.T., Vui D.T., Duyen D.K., Kim Thu D., Thanh Tung B.   +4 more
core   +1 more source

Insights into U‐to‐C RNA editing from the lycophyte Phylloglossum drummondii

The Plant Journal, Volume 119, Issue 1, Page 445-459, July 2024.
Significance Statement U‐to‐C RNA editing is only found in plants, and within plants, only in some hornworts, lycophytes and ferns. The unusual lycophyte Phylloglossum drummondii contains four U‐to‐C editing sites that can be matched with four putative U‐to‐C editing enzymes, making it a useful model for the study of this uncommon process.
Farley M. Kwok van der Giezen, Amy Viljoen, Leni Campbell‐Clause, Nhan Trong Dao, Catherine Colas des Francs‐Small, Ian Small   +5 more
wiley   +1 more source

Huperzia quadrifariata and Huperzia reflexa alkaloids inhibit acetylcholinesterase activity in vivo in mice brain [PDF]

, 2012
Huperzine A, a Lycopodium alkaloid produced by Chinese folk herb Huperzia serrata (Lycopodiaceae), has been shown to be a promising agent for the treatment of Alzheimer's disease due to its potent acetylcholinesterase (AChE) activity, as well its ...
Lunardi, P.S., Henriques, A.T., Neves, Bruna Medeiros, Neves, B.M., Gonçalves, C.A., Ortega, M.G., Passos, Carolina Dos Santos, Henriques, Amalia Teresinha, Passos, C.dos S., Konrath, E.L., Cabrera, J.L., Cabrera, Jose Luis, Ortega, María Gabriela, Lunardi, Paula Santana, Goncalves, C. A., Konrath, Eduardo Luis   +15 more
core   +1 more source

Current state of the epilepsy drug and device pipeline

Epilepsia, Volume 65, Issue 4, Page 833-845, April 2024.
Abstract The field of epilepsy has undergone substantial advances as we develop novel drugs and devices. Yet considerable challenges remain in developing broadly effective, well‐tolerated treatments, but also precision treatments for rare epilepsies and seizure‐monitoring devices.
Samuel W. Terman, Laura Kirkpatrick, Lisa F. Akiyama, Wadih Baajour, Deniz Atilgan, Maria Kristina C. Dorotan, Hyoung Won Choi, Jacqueline A. French   +7 more
wiley   +1 more source