Results 31 to 40 of about 5,858 (232)
Metabolomic Analysis of Goji Berry Sun-Drying: Dynamic Changes in Small-Molecule Substances. [PDF]
FoodsGoji berries (Lycium barbarum L.) are valued for their nutritional and medicinal properties; however, the systematic biochemical impact of drying on their quality remains poorly understood.
Zhang Y +6 more
europepmc +2 more sources
Pharmaceutical Biology, 2023 Context Alkaloid-enriched extract of Huperzia serrata (Thunb.) Trevis (Lycopodiaceae) (HsAE) can potentially be used to manage neuronal disorders.Objective This study determines the anti-neuroinflammatory effects of HsAE on lipopolysaccharide (LPS ...
Thu Kim Dang +8 more
doaj +1 more source
Huperzine A for treatment of cognitive impairment in major depressive disorder: A systematic review of randomized controlled trials [PDF]
, 2016 Background: Acetylcholinesterase (AChE) inhibitors have been shown to be effective in treating cognitive impairment in animal models and in human subjects with major depressive disorder (MDD).
Chiu, Helen +6 more
core +3 more sources
PLoS ONE, 2013 BackgroundHuperzine A is a Chinese herb extract used for Alzheimer's disease. We conducted this review to evaluate the beneficial and harmful effect of Huperzine A for treatment of Alzheimer's disease.MethodsWe searched for randomized clinical trials ...
Guoyan Yang +3 more
doaj +1 more source
Examining the interactome of huperzine A by magnetic biopanning. [PDF]
PLoS ONE, 2012 Huperzine A is a bioactive compound derived from traditional Chinese medicine plant Qian Ceng Ta (Huperzia serrata), and was found to have multiple neuroprotective effects.
Wei Guo +8 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 (1) Background: Huperzine A, a natural cholinesterase (AChE) inhibitor isolated from the Chinese herb Huperzia Serrata, has been used as a dietary supplement in the United States and a drug in China for therapeutic intervention on Alzheimer’s disease (AD)
Yeliang Yan, Jia-Yue Chen, Jiahong Lu
semanticscholar +1 more source
Huperzine A - An Interesting Anticholinesterase Compound from the Chinese Herbal Medicine
Acta Medica, 1998 Huperzine A, alkaloid from the Chinese herbal medicine Qian Ceng Ta, which is prepared from the moss Huperzia serrata, has been used in China for centuries to treat fever and inflammation.
Jiří Patočka
doaj +1 more source
One-step synthesis of Lycopodium alkaloid (-)-huperzine W via Suzuki-Miyaura coupling [PDF]
, 2012 The first total synthesis of (−)-huperzine W (1) has been achieved. Key element of the synthesis is a highly convergent assemblage for the two rings system of target molecule utilizing an efficient Suzuki-Miyaura coupling reaction between chiral iodide 2
Huai-Rong Luo +3 more
core +1 more source
International Journal of Molecular Sciences, 2022 Huperzine A (HupA) is a natural acetylcholinesterase inhibitor (AChEI) with the advantages of high efficiency, selectivity as well as reversibility and can exhibit significant therapeutic effects against certain neurodegenerative diseases.
Hongyu Zhang +5 more
semanticscholar +1 more source
Journal of Fungi, 2023 Huperzine A (HupA) is an important drug for treating Alzheimer’s disease (AD) and is primarily extracted from the Huperzia serrata (Lycopodiaceae). Failures in the chemical synthesis of Hup and in vitro culture have put H. serrata in danger of extinction,
Thanh Thi Minh Le +4 more
doaj +1 more source