Results 21 to 30 of about 1,924 (168)
Current Plant Biology, 2020 Chinese toothed clubmoss (Huperzia serrata) is a primitive fern native in certain types of forests. It is severely endangered in China due to its difficult propagation and massive hunting for huperzine A to improve and prevent Alzheimer’s disease.
Qing-Zhong Peng +4 more
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Neuroprotective Effect of Huperzine A on -Galactose-Induced Hearing Dysfunction
Ear, Nose & Throat Journal, 2021 Background: Administration of d -galactose ( d -gal) has been used to create animal models of neurodegenerative diseases, and huperzine A has been used to treat the neurodegenerative diseases such as Alzheimer disease. Methods: An animal model of hearing
Cong Li MM, Song Shi MD
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Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study [PDF]
PeerJ, 2018 Objective This study was undertaken to detect if free fatty acids (FFA) induce hepatocyte senescence in L-02 cells and if huperzine A has an anti-aging effect in fatty liver cells.
Xiao-na Hu +6 more
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Molecules, 2020 This is the first report of an efficient and effective procedure to optimize the biosynthesis of huperzine A (HupA) and huperzine B (HupB) in vitro from Huperzia selago gametophytes. Axenic tissue cultures were established using spores collected from the
Wojciech J. Szypuła +3 more
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Natural Product Communications, 2021 Huperzine A, isolated from Huperzia serrata, is a potent, specific, and reversible inhibitor of acetylcholinesterase with high efficiency and low toxicity.
Ngoc Chuong Nguyen +5 more
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PLoS ONE, 2013 BackgroundHuperzine A is a Chinese herb extract used for Alzheimer's disease. We conducted this review to evaluate the beneficial and harmful effect of Huperzine A for treatment of Alzheimer's disease.MethodsWe searched for randomized clinical trials ...
Guoyan Yang +3 more
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Huperzine A - An Interesting Anticholinesterase Compound from the Chinese Herbal Medicine
Acta Medica, 1998 Huperzine A, alkaloid from the Chinese herbal medicine Qian Ceng Ta, which is prepared from the moss Huperzia serrata, has been used in China for centuries to treat fever and inflammation.
Jiří Patočka
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Pharmaceutical Biology, 2023 Context Alkaloid-enriched extract of Huperzia serrata (Thunb.) Trevis (Lycopodiaceae) (HsAE) can potentially be used to manage neuronal disorders.Objective This study determines the anti-neuroinflammatory effects of HsAE on lipopolysaccharide (LPS ...
Thu Kim Dang +8 more
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Huperzine A for mild cognitive impairment [PDF]
Cochrane Database of Systematic Reviews, 2010 Mild cognitive impairment (MCI) has been proposed as a condition of intermediate symptomatology between the cognitive changes of ageing and fully developed symptoms of dementia. Treatment in the stages of MCI may delay the deterioration of cognitive impairment and delay the progression to dementia. Currently, the treatments for Alzheimer's disease have
Jirong, Yue +5 more
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Journal of Fungi, 2023 Huperzine A (HupA) is an important drug for treating Alzheimer’s disease (AD) and is primarily extracted from the Huperzia serrata (Lycopodiaceae). Failures in the chemical synthesis of Hup and in vitro culture have put H. serrata in danger of extinction,
Thanh Thi Minh Le +4 more
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