Results 61 to 70 of about 1,873 (124)

The pharmacology and therapeutic potential of (-)-huperzine A

Journal of Experimental Pharmacology, 2012
Maung Kyaw Moe Tun, Seth B HerzonDepartment of Chemistry, Yale University, New Haven, CT, USAAbstract: (–)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss.
Tun MK, Herzon SB
doaj  

How pandemics reshape our brain: Common links and targets between long‐haul COVID‐19, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), oxidative stress, and neurodegeneration

Neuroprotection, Volume 3, Issue 3, Page 280-287, September 2025.
Mary E. Herman
wiley   +1 more source

Huperzine A: a natural acetylcholinesterase inhibitor with multifunctional neuroprotective effects

Beni-Suef University Journal of Basic and Applied Sciences
Background Huperzine A, a naturally derived compound, has garnered interest for its capacity to inhibit cholinesterase with multifaceted neuroprotective effects and is obtained from Huperzia serrata (Chinese club moss plant).
Suvaiv, Kuldeep Singh, Syed Misbahul Hasan, Arun Kumar, Abdullah khan, Mo. Shahanawaz, Syed Mehdi Hasan Zaidi, Kausal Verma   +7 more
doaj   +1 more source

Active anti-acetylcholinesterase component of secondary metabolites produced by the endophytic fungi of Huperzia serrata

Electronic Journal of Biotechnology, 2015
Background: An endophytic fungus lives within a healthy plant during certain stages of, or throughout, its life cycle. Endophytic fungi do not always cause plant disease, and they include fungi that yield different effects, including mutual benefit, and ...
Zhejian Wang, Zhao Ma, Lili Wang, Chengchen Tang, Zhibi Hu, GuiXin Chou, Wankui Li   +6 more
doaj   +1 more source

Development of natural products as drugs acting on central nervous system

Memorias do Instituto Oswaldo Cruz, 1991
We have recenty studied several natural product constituents which have effects on the CNS. (1) Tetrahydropalmatine (THP) and its analogues were isolated from Corydalis ambigua and various species of Stephania.
Xing-Zu Zhu
doaj   +1 more source

Huperzine A provides robust and sustained protection against induced seizures in Scn1a mutant mice

Frontiers in Pharmacology, 2016
De novo loss-of-function mutations in the voltage-gated sodium channel (VGSC) SCN1A (encoding Nav1.1) are the main cause of Dravet syndrome (DS), a catastrophic early-life encephalopathy associated with prolonged and recurrent early-life febrile seizures
Jennifer C. Wong, Stacey B.B. Dutton, Stephen D. Collins, Steven Schachter, Andrew Escayg   +4 more
doaj   +1 more source

Pharmacological treatments for vascular dementia: a systematic review and Bayesian network meta-analysis

Frontiers in Pharmacology
BackgroundVascular dementia (VaD) is one of the most prevalent, burdensome, and costly forms of dementia. Pharmacological treatment is often the first-line choice for clinicians; however, there is a paucity of comparative information regarding the ...
Chun Dang, Qinxuan Wang, Yijia Zhuang, Qian Li, Li Feng, Ying Xiong, Yaoheng Lu   +6 more
doaj   +1 more source

Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease

International Journal of Nanomedicine, 2018
Qingqing Meng,1,* Aiping Wang,1,2,* Hongchen Hua,1 Ying Jiang,1 Yiyun Wang,1 Hongjie Mu,1 Zimei Wu,1 Kaoxiang Sun1 1School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong ...
Meng QQ, Wang AP, Hua HC, Jiang Y, Wang YY, Mu HJ, Wu ZM, Sun KX   +7 more
doaj  

Huperzine A associated with improved early postoperative cognitive function after neurosurgery under general anesthesia: a randomized clinical trial. [PDF]

Int J Surg
Zhang Z, Shen Y, Li J, Tang Y, Zhou P, Ying T, Mo R, Ru Z, Zhao G, Zhu J, Li S, Zhao H.   +11 more
europepmc   +1 more source

Neuroinflammation as a Central Mechanism in Alzheimer's Disease: Therapeutic Insights from Schiff Base Derivatives. [PDF]

Molecules
Abdullah SK, See-Too WS, Mohd Mohidin TB, Mohan G.   +3 more
europepmc   +1 more source