Results 41 to 50 of about 1,873 (124)
Molecules, 2014 A series of Lycopodium alkaloids, namely lycosquarosine A (1), acetylaposerratinine (2), huperzine A (3), huperzine B (4), 8α-hydrophlemariurine B (5), and huperzinine (6), has been isolated from Vietnamese Huperzia squarrosa.
Nguyen Ngoc Chuong +3 more
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Food Science &Nutrition, Volume 14, Issue 5, May 2026.The review examines the nootropic effects of substances used in sports through their impact on neurotransmission, neuroendocrine control, energy production, synaptic plasticity, and neurovascular connections. The four key neurotransmitters dopamine, acetylcholine, serotonin, and GABA function to control motivation, attention, fatigue perception, and ...
Zheng Yi
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Molecules, 2020 This is the first report of an efficient and effective procedure to optimize the biosynthesis of huperzine A (HupA) and huperzine B (HupB) in vitro from Huperzia selago gametophytes. Axenic tissue cultures were established using spores collected from the
Wojciech J. Szypuła +3 more
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Phytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli +4 more
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Recent Advances in Carbonyl–Olefin and Carbonyl–Alkyne Metathesis Reactions
ChemistryEurope, Volume 4, Issue 4, April 2026.Carbonyl–olefin and carbonyl–alkyne metathesis enable atom‐economic C–C bond formation beyond classical olefin metathesis. This review highlights recent advances in photochemical, Lewis‐acid, Brønsted‐acid, and organocatalytic strategies, mechanistic insights, and synthetic applications, showcasing carbonyl metathesis as a versatile platform for modern
Komal Kalonia +2 more
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Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease
Molecules, 2021 Huperzine A (HupA), an alkaloid found in the club moss Huperzia serrata, has been used for centuries in Chinese folk medicine to treat dementia.
María Jesús Friedli +1 more
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Alzheimer's disease drug development pipeline: 2026
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.Abstract INTRODUCTION Discovery and development of new therapies for Alzheimer's disease (AD) are urgently needed to address the world's growing population of individuals on the AD pathophysiological continuum. Clinicaltrials.gov is a resource for studying drugs in development for treatment of AD. RESULTS There are currently 158 drugs in 192 AD trials.
Jeffrey L. Cummings +6 more
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Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.This PROSPERO‐registered review analysed 37 RCTs on neuronutraceuticals for Alzheimer's disease. Despite diverse targets—amyloid/tau, inflammation, oxidative stress, metabolism, synaptic plasticity, cholinergic and hormonal—the evidence was of low quality. RoB2 flagged attrition (86.5%) and reporting bias (81%). Current data do not support clinical use;
Mehmet Akif Topcuoglu, Esen Saka
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Journal of Immunology Research, Volume 2026, Issue 1, 2026.Multiple sclerosis (MS) is a chronic immune‐mediated inflammatory demyelinating disease of the central nervous system (CNS), characterized by multifocal lesions, axonal damage, and progressive neurological dysfunction, imposing a heavy burden on patients and healthcare systems.
Zhiyong Long +6 more
wiley +1 more source
Pharmaceuticals, 2021 This scientific research focused on the production of hydroethanolic extract of the plant species Lycopodium selago L. (L. selago) by the ultrasound-assisted extraction (USAE) and the identification of biocompounds with high antioxidant activity is of ...
Mihai-Vlad Valu +9 more
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