Results 31 to 40 of about 114,626,959 (164)

Microtubules in Spinal Cord Injury: From Cytoskeletal Dysregulation to Therapeutic Regeneration

open access: yesJournal of Neurochemistry, Volume 170, Issue 8, August 2026.
Graphical illustration of the microtubule interactome following spinal cord injury as potential targets for therapy. ABSTRACT Spinal cord injury (SCI) triggers an immediate and sustained disruption of the composition and organization of the neuronal cytoskeleton.
Itzhak Fischer, Peter W. Baas
wiley   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du   +7 more
wiley   +1 more source

The Role of Nootropic Supplements in Sports: Enhancing Cognitive and Physical Performance Simultaneously

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
The review examines the nootropic effects of substances used in sports through their impact on neurotransmission, neuroendocrine control, energy production, synaptic plasticity, and neurovascular connections. The four key neurotransmitters dopamine, acetylcholine, serotonin, and GABA function to control motivation, attention, fatigue perception, and ...
Zheng Yi
wiley   +1 more source

Chemical structure of huperzine A.

open access: yes, 2015
Chemical structure of huperzine A.
Wenjuan Wang (31234)   +10 more
core   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

An improved synthetic route to huperzine A; New analogues and their inhibition of acetylcholinesterase

open access: yes, 1993
A bicycloannulation approach to huperzine A is detailed together with syntheses of the methylene analogue 8, the diamino compound 12 and their inhibition of ...
Kozikowski A. P.   +3 more
core   +1 more source

Recent Advances in Carbonyl–Olefin and Carbonyl–Alkyne Metathesis Reactions

open access: yesChemistryEurope, Volume 4, Issue 4, April 2026.
Carbonyl–olefin and carbonyl–alkyne metathesis enable atom‐economic C–C bond formation beyond classical olefin metathesis. This review highlights recent advances in photochemical, Lewis‐acid, Brønsted‐acid, and organocatalytic strategies, mechanistic insights, and synthetic applications, showcasing carbonyl metathesis as a versatile platform for modern
Komal Kalonia   +2 more
wiley   +1 more source

Alzheimer's disease drug development pipeline: 2026

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.
Abstract INTRODUCTION Discovery and development of new therapies for Alzheimer's disease (AD) are urgently needed to address the world's growing population of individuals on the AD pathophysiological continuum. Clinicaltrials.gov is a resource for studying drugs in development for treatment of AD. RESULTS There are currently 158 drugs in 192 AD trials.
Jeffrey L. Cummings   +6 more
wiley   +1 more source

The chemical structure of Huperzine A.

open access: yes, 2013
The chemical structure of Huperzine A.
Zhang-Qian Wang (403474)   +7 more
core   +1 more source

The scoop on brain health dietary supplement products containing huperzine A

open access: yes, 2020
Context: Public health concerns are emerging surrounding huperzine A commonly found in dietary supplements. We sought to determine the actual content of products claiming to contain huperzine A and whether the ingredients on the supplement facts labels ...
Cindy Crawford (528683)   +5 more
core   +1 more source

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