Results 31 to 40 of about 1,873 (124)

Examining the interactome of huperzine A by magnetic biopanning. [PDF]

PLoS ONE, 2012
Huperzine A is a bioactive compound derived from traditional Chinese medicine plant Qian Ceng Ta (Huperzia serrata), and was found to have multiple neuroprotective effects.
Wei Guo, Shupeng Liu, Jinliang Peng, Xiaohui Wei, Ye Sun, Yangsheng Qiu, Guangwei Gao, Peng Wang, Yuhong Xu   +8 more
doaj   +1 more source

Reference gene selection for real‐time quantitative PCR assays in different tissues of Huperzia serrata based on full‐length transcriptome sequencing

Plant Direct, 2021
Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu, Fei Niu, Hui Jia, Yanli Wang, Bin Guo, Yahui Wei   +5 more
doaj   +1 more source

Detection by UPLC/ESI-TOF-MS of Alkaloids in Three Lycopodiaceae Species from French Polynesia and Their Anticholinesterase Activity

Natural Product Communications, 2009
Three Lycopodiaceae species from French Polynesia, Lycopodium venustulum C. Gaudichaud, Lycopodiella cernua (C. Linnaeus) R. E. Pichi Sermolli and Lycopodium henryanum E. D.
Raimana Ho, Niloufar Marsousi, Philippe Eugster, Jean-Pierre Bianchini, Phila Raharivelomanana   +4 more
doaj   +1 more source

Data on the drug release profiles and powder characteristics of the ethyl cellulose based microparticles prepared by the ultra-fine particle processing system

Data in Brief, 2020
Ethyl cellulose (EC) based microparticles (MPs) could provide sustained release for Huperzine A. The drug release mechanism of MPs was exploited to achieve an ideal drug release profile. We previously found that the wettability of MPs greatly contributed
Tingting Peng, Yin Shi, Chune Zhu, Disang Feng, Xiangyu Ma, Peipei Yang, Xuequn Bai, Xin Pan, Chuan-yu Wu, Wen Tan, Chuanbin Wu   +10 more
doaj   +1 more source

Huperzine A-Liposomes Efficiently Improve Neural Injury in the Hippocampus of Mice with Chronic Intermittent Hypoxia

International Journal of Nanomedicine, 2023
Xin-Yue Yang,1,* Lina Geng,2,* Ronghui Li,2 Ji-Xian Song,1 Cui-Ling Jia,1 Ji-Ren An,1,3 Meng-Fan Sun,1 Shan Xu,1 Ya-Jing Guo,1 Yashuo Zhao,1 En-Sheng Ji1 1Hebei Technology Innovation Center of TCM Combined Hydrogen Medicine, Hebei University of ...
Yang XY, Geng L, Li R, Song JX, Jia CL, An JR, Sun MF, Xu S, Guo YJ, Zhao Y, Ji ES   +10 more
doaj  

Lycodine-Type Alkaloids from Lycopodiastrum casuarinoides and Their Acetylcholinesterase Inhibitory Activity

Molecules, 2014
Four new lycodine-type alkaloids, namely 16-hydroxyhuperzine B (1), N-methyl-11-acetoxyhuperzine B (2), 8,15-dihydrolycoparin A (3) and (7S,12S,13R)-huperzine D-16-O-β-d-glucopyranoside (4), along with ten known analogues 5−14, were isolated from the ...
Dong-Bo Zhang, Jian-Jun Chen, Qiu-Yan Song, Li Zhang, Kun Gao   +4 more
doaj   +1 more source

In Vitro Propagation, Huperzine A Content and Antioxidant Activity of Three Genotypic Huperzia serrata

Plants, 2021
Huperzia serrata is a traditional herb and endangered Chinese medicinal material, which has attracted much attention due to its production of Huperzine A (HupA). In vitro propagation of H.
Yan Yang, Liangfang Dai, Decai Wu, Limin Dong, Yisheng Tu, Jiankun Xie, Xiangdong Luo   +6 more
doaj   +1 more source

Huperzia serrata Extract ‘NSP01’ With Neuroprotective Effects-Potential Synergies of Huperzine A and Polyphenols

Frontiers in Pharmacology, 2021
Huperzia serrata (Thunb.) Trevis is widely used in traditional asiatic medicine to treat many central disorders including, schizophrenia, cognitive dysfunction, and dementia. The major alkaloid, Huperzine A (HA), of H. serrata is a well-known competitive
N. Callizot, ML Campanari, L Rouvière, G Jacquemot, A. Henriques, E Garayev, P. Poindron   +6 more
doaj   +1 more source

The temporal and spatial endophytic fungal community of Huperzia serrata: diversity and relevance to huperzine A production by the host

BMC Microbiology, 2022
Background Plants maintain the steady-state balance of the mutually beneficial symbiosis relationship with their endophytic fungi through secondary metabolites.
Zhuhui Shen, Xubing Liu, Jia Yang, Yanli Wang, Kai Yao, Qingmiao Huo, Yanping Fu, Yahui Wei, Bin Guo   +8 more
doaj   +1 more source

Endophytic Fungal Community of Huperzia serrata: Diversity and Relevance to the Production of Huperzine A by the Plant Host

Molecules, 2021
As the population ages globally, there seem to be more people with Alzheimer’s disease. Unfortunately, there is currently no specific treatment for the disease. At present, Huperzine A (HupA) is one of the best drugs used for the treatment of Alzheimer’s
Lingli Cui, Hamza Armghan Noushahi, Yipeng Zhang, Jinxin Liu, Andreea Cosoveanu, Ying Liu, Ling Yan, Jing Zhang, Shaohua Shu   +8 more
doaj   +1 more source