Results 21 to 30 of about 1,873 (124)
Neuroprotective Effect of Huperzine A on -Galactose-Induced Hearing Dysfunction
Ear, Nose & Throat Journal, 2021 Background: Administration of d -galactose ( d -gal) has been used to create animal models of neurodegenerative diseases, and huperzine A has been used to treat the neurodegenerative diseases such as Alzheimer disease. Methods: An animal model of hearing
Cong Li MM, Song Shi MD
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Current Plant Biology, 2020 Chinese toothed clubmoss (Huperzia serrata) is a primitive fern native in certain types of forests. It is severely endangered in China due to its difficult propagation and massive hunting for huperzine A to improve and prevent Alzheimer’s disease.
Qing-Zhong Peng +4 more
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Natural Product Communications, 2021 Huperzine A, isolated from Huperzia serrata, is a potent, specific, and reversible inhibitor of acetylcholinesterase with high efficiency and low toxicity.
Ngoc Chuong Nguyen +5 more
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PLoS ONE, 2013 BackgroundHuperzine A is a Chinese herb extract used for Alzheimer's disease. We conducted this review to evaluate the beneficial and harmful effect of Huperzine A for treatment of Alzheimer's disease.MethodsWe searched for randomized clinical trials ...
Guoyan Yang +3 more
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Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study [PDF]
PeerJ, 2018 Objective This study was undertaken to detect if free fatty acids (FFA) induce hepatocyte senescence in L-02 cells and if huperzine A has an anti-aging effect in fatty liver cells.
Xiao-na Hu +6 more
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Journal of Fungi, 2023 Huperzine A (HupA) is an important drug for treating Alzheimer’s disease (AD) and is primarily extracted from the Huperzia serrata (Lycopodiaceae). Failures in the chemical synthesis of Hup and in vitro culture have put H. serrata in danger of extinction,
Thanh Thi Minh Le +4 more
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Huperzine A - An Interesting Anticholinesterase Compound from the Chinese Herbal Medicine
Acta Medica, 1998 Huperzine A, alkaloid from the Chinese herbal medicine Qian Ceng Ta, which is prepared from the moss Huperzia serrata, has been used in China for centuries to treat fever and inflammation.
Jiří Patočka
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Drug Delivery, 2020 Increasingly attention has been paid to the transdermal drug delivery systems with microneedles owing to their excellent compliance, high efficiency, and controllable drug release, therefore, become promising alternative with tremendous advantages for ...
Qinying Yan +9 more
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Physiological Reports, 2022 Acetylcholine (ACh) may be involved in the regulation of ovarian functions. A previous systemic study in rats showed that a 4‐week, intrabursal local delivery of the ACh‐esterase blocker Huperzine‐A increased intraovarian ACh levels and changed ovarian ...
Fernanda C. Cuevas +8 more
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Isolation and purification of Huperzine A
浙江大学学报. 农业与生命科学版, 2002 Technique of isolation and purification of Huperzine A from Huperzia serrata (Thunb) Trev. was studied in this paper. To get rid of some pigments and other impurities, some of chemical techniques for separation such as extraction with organic acid ...
SHEN Sheng-rong +3 more
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