Results 81 to 90 of about 4,013 (114)

Single-cell RNA sequencing analysis reveals the critical role of fibroblasts in aortic progeria-associated vascular remodeling in Hutchinson-Gilford progeria syndrome mice. [PDF]

Front Immunol
Sun Q, Yang L, Zhou Z, Wu N, Li C, Hu Q, Cong X.   +6 more
europepmc   +1 more source

Cardiac and skeletal muscle manifestations in the G608G mouse model of Hutchinson-Gilford progeria syndrome. [PDF]

Aging Cell
Hong Y, Rannou A, Manriquez N, Antich J, Liu W, Fournier M, Omidfar A, Rogers RG.   +7 more
europepmc   +1 more source

Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome. [PDF]

APL Bioeng
Abutaleb NO, Gao XD, Bedapudi A, Choi L, Shores KL, Kennedy C, Duby JE, Cao K, Liu DR, Truskey GA.   +9 more
europepmc   +1 more source

Delayed localization of A-type lamins to the rupture sites in Hutchinson–Gilford progeria syndrome

, 2023
Kono Y, Pack C, Ichikawa T, Komatsubara A, Adam SA, Miyazawa K, Rolas L, Nourshargh S, Medalia O, Goldman RD, Fukuma T, Kimura H, Shimi T.   +12 more
europepmc   +1 more source

Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome. [PDF]

Front Cardiovasc Med
Gordon LB, Basso S, Maestranzi J, Aikawa E, Clift CL, Cammardella AG, Danesi TH, Del Nido PJ, Edelman ER, Hamdy A, Hegde SM, Kleinman ME, Maschietto N, Mehra MR, Mukundan S, Musumeci F, Russo M, Rybicki FJ, Shah PB, Suarez WA, Tuminelli K, Zaleski K, Prakash A, Gerhard-Herman M.   +23 more
europepmc   +1 more source

Mitophagy defect mediates the aging-associated hallmarks in Hutchinson-Gilford progeria syndrome. [PDF]

Aging Cell
Sun Y, Xu L, Li Y, Jia S, Wang G, Cen X, Xu Y, Cao Z, Wang J, Shen N, Hu L, Zhang J, Mao J, Xia H, Liu Z, Fu X.   +15 more
europepmc   +1 more source

Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome. [PDF]

J Clin Invest
Barettino A, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Guerrero CR, Espinosa FM, Carmona RM, Blanco Y, Dorado B, Torroja C, Sánchez-Cabo F, Quintas A, Benguría A, Dopazo A, García R, Benedicto I, Andrés V.   +16 more
europepmc   +1 more source

Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome. [PDF]

J Am Heart Assoc
Olsen FJ, Biering-Sørensen T, Lunze F, Hegde SM, Colan SD, Ehrbar R, Massaro J, Ferraro AM, Harrild DM, Kleinman ME, Gordon LB, Prakash A.   +11 more
europepmc   +1 more source

Hutchinson-Gilford progeria syndrome: unraveling the genetic basis, symptoms, and advancements in therapeutic approaches. [PDF]

Ther Adv Rare Dis
Arun A, Nath AR, Thankachan B, Unnikrishnan MK.   +3 more
europepmc   +1 more source

The anti-senescence effect of D-β-hydroxybutyrate in Hutchinson-Gilford progeria syndrome involves progerin clearance by the activation of the AMPK-mTOR-autophagy pathway. [PDF]

Geroscience
Monterrubio-Ledezma F, Salcido-Gómez A, Zavaleta-Vásquez T, Navarro-García F, Cisneros B, Massieu L.   +5 more
europepmc   +1 more source