Results 91 to 100 of about 7,521 (211)
Clinicopathological Challenge: A Progressively Enlarging Hardened Skin Plaque
International Journal of Dermatology, Volume 65, Issue 1, Page 15-17, January 2026.ABSTRACT Stiff skin syndrome (SSS) is a rare connective tissue disease manifesting as a progressive, non‐inflammatory fibrosis that causes the skin and soft tissues to harden. It can result in restricted joint movement, particularly affecting the shoulder and pelvic girdle. A segmental variant with a better prognosis has been described.
Marian Fernández Martínez +3 more
wiley +1 more source
Cellular Senescence, Inflammaging and Cardiovascular Disease
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT Aging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long‐term cardiovascular health. This review summarizes current knowledge on the effects of aging within the cardiovascular system as well as systemic processes ...
Lukas Zanders +3 more
wiley +1 more source
Ocular manifestations in the Hutchinson-Gilford progeria syndrome
Indian Journal of Ophthalmology, 2011 The Hutchinson-Gilford progeria (HGP) syndrome is an extremely rare genetic condition characterized by an appearance of accelerated aging in children. The word progeria is derived from the Greek word progeros meaning ′prematurely old′. It is caused by de
Shivcharan L Chandravanshi +3 more
doaj +1 more source
DNA damage: A main determinant of vascular aging [PDF]
, 2016 Vascular aging plays a central role in health problems and mortality in older people. Apart from the impact of several classical cardiovascular risk factors on the vasculature, chronological aging remains the single most important determinant of ...
Bautista-Niño, P.K. (Paula) +4 more
core +2 more sources
Advanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam +7 more
wiley +1 more source
, 2015 We perform a statistical study of the distances between successive occurrencies of a given dinucleotide in the DNA sequence for a number of organisms of different complexity.
Castellani, Gastone C. +6 more
core +1 more source
Structure and stability of the lamin A tail domain and HGPS mutant [PDF]
, 2011 Hutchinson–Gilford progeria syndrome (HGPS) is a premature aging syndrome caused by the expression and accumulation of a mutant form of lamin A, Δ50 lamin A.
Buehler, Markus J +3 more
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Syndrome Hutchinson-Gilford (progeria)
Problems of Endocrinology, 1995 Gatchinson-Guildford syndrome or progeria (senile dwarfism) is an extremely rare genetic disease in children with clinical features of premature aging. The frequency of the disease is 1 in 8 million newborns (De Busk. 1972). To date, about 70 patients with this syndrome have been described in world literature. The etiology of progeria is unclear.
openaire +2 more sources
Indian Journal of Dental Research, 2009 Hutchinson Gilford Progeria Syndrome (HGPS) is a rare, sporadic, autosomal dominant syndrome that involves premature ageing and death at early age due to myocardial infarction or stroke.
Mohamed Riyaz S, Jayachandran S
doaj
Hutchinson-Gilford Progeria Syndrome: A Rare Genetic Disorder
Case Reports in Dentistry, 2013 Hutchinson-Gilford progeria syndrome (HGPS) is a rare pediatric genetic syndrome with incidence of one per eight million live births. The disorder is characterised by premature aging, generally leading to death at approximately 13.4 years of age. This is
Rajat G. Panigrahi +7 more
doaj +1 more source