Results 81 to 90 of about 1,306,775 (184)
Cell Reports, 2014 Summary: Advanced age and DNA damage accumulation are prominent risk factors for cancer. The premature aging disorder Hutchinson-Gilford progeria syndrome (HGPS) provides a unique opportunity for studying the interplay between DNA damage and aging ...
Patricia Fernandez +5 more
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Hutchinson-Gilford syndrome (progeria)
Indian Journal of Dermatology, 2009 Progeria is a rare, autosomal dominant, progeroid disorder. In the world literature less than 100 cases have been reported to date. We present this case because of its rarity.
Surjushe Amar +3 more
doaj
Hutchinson-Gilford progeria syndrome: Rejuvenating old drugs to fight accelerated ageing
, 2020 International audienceWhat if the next generation of successful treatments was hidden in the current pharmacopoeia? Identifying new indications for existing drugs, also called the drug repurposing or drug rediscovery process, is a highly efficient and ...
Muchir, Antoine +4 more
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Progeroid Syndrome and Mutation in LMNA Gene: Report of Two Cases from Iran [PDF]
Journal of Kerman University of Medical Sciences, 2005 Two Iranian cases with very rare progeroid syndrome are reported. The first is a 24-year-old girl who has been healthy till her 13th birthday. From that time she has been suffering from a progressive generalized and multi-systemic illness.
Y Shafeghati, N Levy, G.M Martin
doaj
Aging in the Cardiovascular System: Lessons from Hutchinson-Gilford Progeria Syndrome [PDF]
, 2018 Aging, the main risk factor for cardiovascular disease (CVD), is becoming progressively more prevalent in our societies. A better understanding of how aging promotes CVD is therefore urgently needed to develop new strategies to reduce disease burden ...
del Campo, Lara +5 more
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Syndrome Hutchinson-Gilford (progeria)
Problems of Endocrinology, 1995 Gatchinson-Guildford syndrome or progeria (senile dwarfism) is an extremely rare genetic disease in children with clinical features of premature aging. The frequency of the disease is 1 in 8 million newborns (De Busk. 1972). To date, about 70 patients with this syndrome have been described in world literature. The etiology of progeria is unclear.
openaire +2 more sources
Radiological Diagnosis of a Rare Premature Aging Genetic Disorder: Progeria (Hutchinson-Gilford Syndrome) [PDF]
, 2017 Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare disease with a combination of short stature, bone abnormalities, premature ageing, and skin changes. Though the physical appearance of these patients is characteristic, there is little emphasis on the
Haji Mohammed Nazir +3 more
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Clinical imaging findings in a girl with Hutchinson-Gilford progeria syndrome
, 2012 [[abstract]]"Clinical imaging findings in a girl with Hutchinson-Gilford progeria syndrome: We report an 8½-year-old girl with premature aging, a karyotype of 46,XX and a de novo c.1824C>T mutation encoding p.G608G in the lamin A gene.
陳持平;Chen, Chih-Ping
core
Altered Nuclear Functions in Progeroid Syndromes: a Paradigm for Aging Research
The Scientific World Journal, 2009 Syndromes of accelerated aging could provide an entry point for identifying and dissecting the cellular pathways that are involved in the development of age-related pathologies in the general population.
Baomin Li +4 more
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Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome
Bone, 2019 Children with Hutchinson-Gilford progeria syndrome (HGPS), a rare premature aging disease, exhibit extraskeletal calcifications detected by radiographic analysis and on physical examination. The aim of this study was to describe the natural history and pathophysiology of these abnormal calcifications in HGPS, and to determine whether medications and/or
C M, Gordon +12 more
openaire +3 more sources