Results 131 to 140 of about 4,224 (165)

Hutchinson-Gilford progeria syndrome

Drugs of the Future, 2006
The rare genetic autosomal dominant condition Hutchinson-Gilford progeria syndrome (HGPS) is characterized by a dramatic, rapid appearance of aging beginning in childhood. HGPS progression generates vascular disease, which generally leads to death during the teenage years.
null Davies, S.L., null Bozzo, J.
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Cardiovascular manifestations of Hutchinson–Gilford progeria syndrome

Cardiology in the Young, 2022
AbstractCardiovascular complications are the most frequent cause of death in patients with the Hutchinson–Gilford progeria syndrome. However, due to its rarity, studying the course of cardiac abnormalities has been a challenge. The cardiovascular phenotype helps to provide greater insight into the natural history of these abnormalities.
Andreia Palma, Patrícia V. Silva, António Pires   +2 more
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Hutchinson–Gilford Progeria Syndrome

JAMA Dermatology
This case report describes a boy younger than 2 years with Hutchinson–Gilford progeria syndrome.
Yu-Ting, Tsai, Yi-Chien, Yang
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Hutchinson-Gilford Progeria Syndrome

2019
The Hutchinson-Gilford syndrome or progeria is a laminopathy generated by mutations that affect LMNA gene. This produces an abnormal protein named progerine which alters the formation of the cellular membrane inducing premature aging of all cells. In the present review aspects related to the pathophysiology and clinical characteristics of this syndrome
Camacho-Cruz, Jhon, Dary Gutiérrez-Castañeda, Luz, Pulido, Daniela, Echeverri, Catalina, Bernal, Betty, Bautista, Luisa, Angarita, Lizeth, Villamil, Andrés, Guarin, Laura, Benavides, Vanessa, Lancheros, Natalia, Pardo, Juan, Bautista, Monica   +12 more
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Hyaluronuria in a Case of Progeria (Hutchinson‐Gilford Syndrome)

Journal of the American Geriatrics Society, 1978
ABSTRACT A classic case of progeria (Hutchinson‐Gilford syndrome) in a 9‐year‐old Japanese boy is presented. The characteristic clinical features in this patient were similar to those reported in the literature.
M, Tokunaga, E, Wakamatsu, K, Sato, S, Satake, K, Aoyama, K, Saito, M, Sugawara, Z, Yosizawa   +7 more
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Patient with unusual Hutchinson-Gilford syndrome (progeria)

Pediatric Neurology, 1994
A patient with unusual Hutchinson-Gilford syndrome (progeria) is reported. This 7-year-old boy had all the characteristics of progeria, except for coxa valga and the "horse-riding" stance. A previous cerebral infarction was detected in the right putamen on cranial magnetic resonance imaging.
S, Matsuo, Y, Takeuchi, S, Hayashi, A, Kinugasa, T, Sawada   +4 more
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Hutchinson-Gilford progeria syndrome.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1999
Hutchinson-Gilford progeria syndrome is an extremely rare condition of premature aging. It is characterized by growth retardation and accelerated degenerative changes of cutaneous, musculoskeletal and cardiovascular systems. The pathogenesis of the disease is unknown. The patients usually appear normal at birth. Typical manifestations develop gradually
W, Wisuthsarewong, S, Viravan
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Hutchinson-Gilford Progeria Syndrome

Southern Medical Journal, 1978
P, Runge, M S, Asnis, G W, Brumley, H, Grossman   +3 more
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Hip Disease in Hutchinson-Gilford Progeria Syndrome

Journal of Pediatric Orthopaedics, 1984
Two cases of Hutchinson-Gilford progeria syndrome are presented with a focus on hip disease. A severe coxa valga is the first abnormality. The femoral head becomes increasingly uncovered as the acetabulum becomes more dysplastic. The center edge angle decreases, the acetabular index increases, and the medial wall of the acetabulum widens.
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Vascular dysfunction in Hutchinson–Gilford progeria syndrome

Trends in Molecular Medicine
Most patients with Hutchinson-Gilford progeria syndrome (HGPS) succumb to cardiovascular disease. Recent studies by Barettino et al., Cardoso et al., and Vakili et al. utilized progeria mouse models to elucidate novel mechanisms by which vascular smooth muscle cell (VSMC) and endothelial cell (EC) dysfunction accelerate the progress of the disease ...
Yaping Zhao, Li Wang, Suowen Xu
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