Results 51 to 60 of about 77,921 (314)

The single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene influences endothelial cell function : Interaction with selenium and fatty acids [PDF]

, 2013
© 2013 The Authors. Molecular Nutrition & Food Research published by Wiley-VCH Verlag GmbH & Co.
Akbaraly, Bellinger, Bermano, Bermano, Björnstedt, Brigelius-Flohé, Brigelius-Flohé, Drummen, Gautrey, Gong, Gu, Hayden, Hesketh, Kretz-Remy, Libby, Lubos, Mata, Mayer, Miller, Mozaffarian, Méplan, Phillips, Polonikov, Rayman, Sneddon, Sneddon, Sneddon, Sutherland, Thies, To, Udler, Villette   +31 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

European Journal of Histochemistry, 2022
Atherosclerosis is a disease in which lipids and inflammatory factors accumulate on the walls of arteries, forming plaques that eventually block the flow of blood.
Dajie Wang, Zhaofeng Zhou, Liang Yuan
doaj   +1 more source

Shear stress regulation of miR-93 and miR-484 maturation through nucleolin. [PDF]

, 2019
Pulsatile shear (PS) and oscillatory shear (OS) elicit distinct mechanotransduction signals that maintain endothelial homeostasis or induce endothelial dysfunction, respectively.
Chen, Lili, Chen, Shanshan, Chien, Shu, Gongol, Brendan, Han, Yue, He, Ming, Huang, Po-Hsun, Johnson, David A, Kang, Jian, Li, Jie, Li, Yi-Shuan, Liu, Jun-Hui, Lytle, Christian, Marin, Traci, Martin, Marcy, Shyy, John Y-J, Sun, Wei, Wang, Shen-Chih, Zhang, Jiao   +18 more
core  

Atrial Natriuretic Peptide Protects against Histamine-Induced Endothelial Barrier Dysfunction in Vivo [PDF]

, 2008
Endothelial barrier dysfunction is a hallmark of many severe pathologies, including sepsis or atherosclerosis. The cardiovascular hormone atrial natriuretic peptide (ANP) has increasingly been suggested to counteract endothelial leakage.
Bihari, Peter, Bubik, Martin F., Fürst, Robert, Hoffmann, Florian, Khandoga, Alexander G., Krombach, Fritz, Mayer, Bettina A., Rehberg, Markus, Vollmar, Angelika M., Zahler, Stefan   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Parmodulins Inhibit Thrombus Formation Without Inducing Endothelial Injury Caused by Vorapaxar [PDF]

, 2015
Protease-activated receptor-1 (PAR1) couples the coagulation cascade to platelet activation during myocardial infarction and to endothelial inflammation during sepsis. This receptor demonstrates marked signaling bias.
Ahn, Andrade-Gordon, Andrews, Bae, Bae, Bae, Bernatowicz, Capodanno, Chackalamannil, Chandra C. Ghosh, Chris Dockendorff, Christian G. Peters, Connolly, Covic, Dockendorff, Dowal, Garcia, Griffin, James R. Dilks, Karen De Ceunynck, Kataoka, Katritch, Knezevic, Kosoglou, Kosoglou, Lee, Matsuoka, May, McCoy, Mingdong Huang, Moers, Morrow, Mosnier, Mosnier, Mosnier, Nicholls, Offermanns, Omozuanvbo Aisiku, O’Callaghan, O’Donoghue, Riewald, Riewald, Robert Flaumenhaft, Salchow, Samir M. Parikh, Susanna F. Fustolo-Gunnink, Swift, Taylor, Tressel, Tricoci, Vanhoorelbeke, Wiviott, Zhang   +52 more
core   +2 more sources

Synthesis of a Novel Thermoresponsive S53P4 Bioactive Glass Extract–Poloxamer 407 Injectable Hydrogels: Assessment of Biocompatibility and Antimicrobial Properties

Advanced Engineering Materials, EarlyView.
This study investigates innovative thermoreversible hydrogels derived from S53P4 bioactive glass extracts to aid in the healing of infected diabetic foot wounds. These injectable gels, which gel at body temperature, release beneficial ions and remain stable over time.
Marian G. Vargas Guerrero, Adrian Stiller, Alex Nygård, Matej Krivulka, Lars Galema, Erwin Peters, Jimmy Lucchesi, Peter Uppstu, Leena Hupa, Jacobus J. C. Arts   +9 more
wiley   +1 more source

Hyaluronic acid alters vessel behavior in CXCL12-treated HUVECs [PDF]

, 2018
Hyaluronic acid (HA) is a key component of the extracellular matrix known for absorbing water, swelling, and altering solid stress of tumors. HA’s anionic behavior may provide important biochemical effects toward tumor progression as well.
Seibel, Alex J.
core  

Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression. [PDF]

, 2012
Vascular cell adhesion molecule-1 (VCAM-1) plays important roles in development and inflammation. Tumor necrosis factor-α (TNF-α) and focal adhesion kinase (FAK) are key regulators of inflammatory and integrin-matrix signaling, respectively.
Chen, Xiao Lei, Cheresh, David A, Lawson, Christine, Lim, Ssang-Taek, Miller, Nichol LG, Schlaepfer, David D, Tancioni, Isabelle, Uryu, Sean, Walsh, Colin T, Weis, Sara M   +9 more
core   +1 more source