Results 1 to 10 of about 128,726 (309)

A modified protocol for the isolation and culture of human umbilical vein endothelial cells [PDF]

Biochemistry and Biophysics Reports
The umbilical cord is a valuable source of foetal stem cells, progenitor cells, and early-stage developmental cells, including human umbilical vein endothelial cells (HUVECs). HUVECs are widely used as a model for endothelial biology and are increasingly
Anmol Sandhu, Anannya Parvathi, Jennifer Jane McGhee, Salim Ismail, I-Ping Loh, Bert van der Werf, Jie Zhang, Trevor Sherwin   +7 more
doaj   +2 more sources

Effects of Arthrospira platensis on Human Umbilical Vein Endothelial Cells. [PDF]

Life (Basel)
Atherosclerosis is initiated by injury or damage to the vascular endothelial cell monolayer. Therefore, the early repair of the damaged vascular endothelium by a proliferation of neighbouring endothelial cells is important to prevent atherosclerosis and thrombotic events.
Krüger-Genge A, Harb K, Braune S, Jung CHG, Westphal S, Bär S, Mauger O, Küpper JH, Jung F.   +8 more
europepmc   +4 more sources

Double suicide genes selectively kill human umbilical vein endothelial cells [PDF]

Virology Journal, 2011
Background To construct a recombinant adenovirus containing CDglyTK double suicide genes and evaluate the killing effect of the double suicide genes driven by kinase domain insert containing receptor (KDR) promoter on human umbilical vein endothelial ...
Liu Lunxu, Wang Yanping, Mei Longyong, Jia Weiguo, Che Guowei   +4 more
doaj   +3 more sources

Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs

Molecular Therapy: Nucleic Acids, 2021
Atherosclerosis is the main cause of cardio-cerebrovascular diseases. Endothelial-mesenchymal transition plays an important role in atherosclerosis. Icariin has a protective effect on atherosclerosis; however, the underlying mechanism remains unclear. In
Shan Liu, Dong-sheng Xu, Min Li, Yang Zhang, Qi Li, Teng-teng Li, Li-qun Ren   +6 more
doaj   +1 more source

Aberrant expression of proatherogenic cytokines and growth factors in human umbilical vein endothelial cells from newborns of type 2 diabetic women

SAGE Open Medicine, 2021
Objectives: This study reports the levels of cytokines, chemokines, and growth factors previously identified as taking part in the pathology of atherosclerosis in human umbilical vein endothelial cells derived from mothers with type 2 diabetes and ...
Samar Sultan
doaj   +1 more source

Proteoglycans from human umbilical vein endothelial cells [PDF]

European Journal of Biochemistry, 1987
Human umbilical vein endothelial cells were incubated with [35S]sulphate and investigated for their proteoglycan production. By gel chromatography, ion-exchange chromatography and CsCl density-gradient centrifugation we obtained preparative amounts of the endothelial proteoheparan sulphate HSI and of proteochondroitin sulphate from the conditioned ...
A, Griesmacher, R, Hennes, R, Keller, H, Greiling   +3 more
openaire   +2 more sources

Triptolide Alleviates Oxidized LDL-Induced Endothelial Inflammation by Attenuating the Oxidative Stress-Mediated Nuclear Factor-Kappa B Pathway

Current Therapeutic Research, 2022
Background: Endothelial inflammation triggered by oxidized LDL (ox-LDL) is a crucial mechanism involved in atherosclerosis. Triptolide (TP), a primary active ingredient of the traditional Chinese medicine Tripterygium wilfordii Hook F, possesses ...
Shiyu Zhang, MD, Shiyang Xie, MD, Yuan Gao, MD, Youping Wang, MD, PhD   +3 more
doaj   +1 more source

Adaptive induction of growth differentiation factor 15 attenuates endothelial cell apoptosis in response to high glucose stimulus. [PDF]

PLoS ONE, 2013
Growth differentiation factor 15 (GDF15), a direct target gene of p53, is a multifunctional member of the TGF-β/BMP superfamily. GDF15 can be induced and is implicated as a key secretory cytokine in response to multiple cellular stimuli.
Jun Li, Lijun Yang, Weijun Qin, Geng Zhang, Jianlin Yuan, Fuli Wang   +5 more
doaj   +1 more source

Human umbilical vein endothelial cells secrete transcobalamin II [PDF]

Blood, 1990
Abstract Transcobalamin II (TC II) is essential for cellular uptake of cobalamin. However, the origin of this transport protein is controversial and many organ sources have been suggested. We studied human umbilical vein endothelial cells cultured in vitro.
R, Carmel, S M, Neely, R B, Francis
openaire   +3 more sources

Isolation of Human Umbilical Vein Endothelial Cells (HUVEC) [PDF]

Journal of Visualized Experiments, 2007
Angiogenesis is a complex multi-step process, where in response to angiogenic stimuli, new vessels are created from the existing vasculature. These steps include: degradation of the basement membrane, proliferation and migration (sprouting) of endothelial cells (EC) into the extracellular matrix, alignment of EC into cords, lumen formation, anastomosis,
Steve P, Crampton, Jaeger, Davis, Christopher C W, Hughes   +2 more
openaire   +2 more sources