Results 151 to 160 of about 114,431 (323)
Effects of Therapeutic Targeting of Cancer Associated Fibroblasts on Extracellular Matrix Remodeling in an Engineered Tumor Stroma Model [PDF]
, 2018 The tumor microenvironment (TME) is a complex combination of stromal cells and extracellular matrix. The cancer-associated fibroblast (CAF) plays an integral role in remodeling the TME and promoting tumor aggression.
Chang, Jonathan
core
Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation
Small Structures, EarlyView.GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee +4 more
wiley +1 more source
Pathogenesis of Vitiligo: Integrating Immune and Non‐Immune Cell Crosstalk
The Journal of Dermatology, EarlyView.ABSTRACT Vitiligo is an acquired autoimmune disease characterized by depigmented macules resulting from melanocyte loss. It is a complex multifactorial disorder in which genetic predisposition is combined with environmental factors; however, its detailed etiology remains unclear.
Shintaro Inoue
wiley +1 more source
Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion
Artificial Organs, EarlyView.This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht +4 more
wiley +1 more source
Results of Chondrocyte Implantation with a Fibrin-Hyaluronan Matrix: A Preliminary Study [PDF]
, 2008 Stefan Nehrer +4 more
openalex +1 more source
Equine experimental lameness induction models
Equine Veterinary Education, EarlyView.Summary Equine lameness due to musculoskeletal injury remains a common and significant cause of decreased performance. While our understanding and management of lameness have improved with advanced imaging, as well as diagnostic and therapeutic progression, a need for experimental equine models of lameness remains.
A. Dockery, B. Beasley, V. J. Moorman
wiley +1 more source
Hyaluronan Regulates Cell Behavior: A Potential Niche Matrix for Stem Cells
Biochemistry Research International, 2012 Hyaluronan is a linear glycosaminoglycan that has received special attention in the last few decades due to its extraordinary physiological functions.
Mairim Alexandra Solis +5 more
doaj +1 more source
Equine Veterinary Education, EarlyView.Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley +1 more source
Scientific ReportsClostridium perfringens, an opportunistic pathogen, produces mu-toxin hyaluronidases including endo-β-N-acetylglucosaminidases (Nags) as a virulence invasion factor.
Tomoya Kumon +2 more
doaj +1 more source
The FEBS Journal, EarlyView.CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson +10 more
wiley +1 more source