Results 51 to 60 of about 114,431 (323)
International Journal of Cell Biology, 2015 Hyaluronan is a negatively charged polydisperse polysaccharide where both its size and tissue concentration play an important role in many physiological and pathological processes. The various functions of hyaluronan depend on its molecular size.
Lan Do +8 more
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Phospholipids and Hyaluronan: From Molecular Interactions to Nano- and Macroscale Friction
Colloids and Interfaces, 2022 Phospholipids and hyaluronan are two key biomolecules that contribute to the excellent lubrication of articular joints. Phospholipids alone and in combination with hyaluronan have also displayed low friction forces on smooth surfaces in micro- and ...
Sixuan Li +4 more
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Hyaluronan: Biosynthesis and signaling [PDF]
, 2014 Background Hyaluronan is a critical component of extracellular matrix with several different roles. Besides the contribution to the tissue hydration, mechanical properties and correct architecture, hyaluronan plays important biological functions ...
De Luca, G. +5 more
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Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis
Science Translational Medicine, 2019 Hepatic stellate cells activated by hyaluronan synthase 2–mediated hyaluronan and Notch1 promote liver fibrosis, identifying a potential target. HAlting liver fibrosis Hepatic stellate cells (HSCs) play a key role in liver fibrosis, a process marked by ...
Y. Yang +19 more
semanticscholar +1 more source
Polymers, 2020 A high-molecular weight hyaluronan is oxidatively degraded by Cu(II) ions and ascorbate—the so called Weissberger biogenic oxidative system—which is one of the most potent generators of reactive oxygen species, namely •OH radicals.
K. Valachová +6 more
semanticscholar +1 more source
Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology
International Journal of Cell Biology, 2015 Hyaluronan signaling properties are unique among other biologically active molecules, that they are apparently not influenced by postsynthetic molecular modification, but by hyaluronan fragment size. This review summarizes the current knowledge about the
Jaime M. Cyphert +2 more
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Multiscale modelling of fluid and solute transport in soft tissues and microvessels [PDF]
, 2010 This study focuses on the movement of particles and extracellular fluid in soft tissues and microvessels. It analyzes modeling applications in biological and physiological fluids at a range of different length scales: from between a few tens to several ...
Lu, Yiling, Wang, Wen
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The hyaluronan-binding serine protease from human plasma cleaves HMW and LMW kininogen and releases bradykinin [PDF]
, 2002 The influence of the hyaluronanbinding protease (PHBSP), a plasma enzyme with FVII- and pro-urokinase-activating potency, on components of the contact phase (kallikrein/kinin) system was investigated.
Beer, N. +4 more
core +1 more source
Marine Biomaterials: Hyaluronan
Marine Drugs, 2023 The marine-derived hyaluronic acid and other natural biopolymers offer exciting possibilities in the field of biomaterials, providing sustainable and biocompatible alternatives to synthetic materials. Their unique properties and abundance in marine sources make them valuable resources for various biomedical and industrial applications.
Rasha. M. Abdel-Rahman +1 more
openaire +3 more sources
LYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan
Journal of Cell Biology, 1999 The extracellular matrix glycosaminoglycan hyaluronan (HA) is an abundant component of skin and mesenchymal tissues where it facilitates cell migration during wound healing, inflammation, and em- bryonic morphogenesis.
Suneale Banerji +7 more
semanticscholar +1 more source