Results 51 to 60 of about 81,827 (314)
Low Molecular Mass Myocardial Hyaluronan in Human Hypertrophic Cardiomyopathy
Cells, 2019 During the development of hypertrophic cardiomyopathy, the heart returns to fetal energy metabolism where cells utilize more glucose instead of fatty acids as a source of energy.
Christina E. Lorén +6 more
doaj +1 more source
Role of the ratio of biopolyelectrolyte persistence length to nanoparticle size in the structural tuning of electrostatic complexes [PDF]
Physical Review E, American Physical Society (APS), 2016, 94
(032504), 2016 Aggregation of nanoparticles of given size $R$ induced by addition of a polymer strongly depends on its degree of rigidity. This is shown here on a large variety of silica nanoparticle self-assemblies obtained by electrostatic complexation with carefully selected oppositely charged bio-polyelectrolytes of different rigidity.
arxiv +1 more source
Hyaluronic acid: perspectives in upper aero-digestive tract. A systematic review [PDF]
, 2015 Background: To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper aerodigestive tract (UADT).
Baptista, Peter +7 more
core +3 more sources
Hyaluronan and the Fascial Frontier [PDF]
International Journal of Molecular Sciences, 2021 The buzz about hyaluronan (HA) is real. Whether found in face cream to increase water volume loss and viscoelasticity or injected into the knee to restore the properties of synovial fluid, the impact of HA can be recognized in many disciplines from dermatology to orthopedics.
openaire +3 more sources
International Journal of Cell Biology, 2015 Hyaluronan is a negatively charged polydisperse polysaccharide where both its size and tissue concentration play an important role in many physiological and pathological processes. The various functions of hyaluronan depend on its molecular size.
Lan Do +8 more
doaj +1 more source
Single-molecule stretching shows glycosylation sets tension in the hyaluronan-aggrecan bottlebrush [PDF]
, 2019 Large bottlebrush complexes formed from the polysaccharide hyaluronan (HA) and the proteoglycan aggrecan contribute to cartilage compression resistance and are necessary for healthy joint function. A variety of mechanical forces act on these complexes in the cartilage extracellular matrix, motivating the need for a quantitative description which links ...
arxiv +1 more source
Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics. [PDF]
Nat CommunImmune surveillance involves the continual migration of antigen-scavenging immune cells from the tissues to downstream lymph nodes via lymphatic vessels.
Bano F +11 more
europepmc +2 more sources
Drug conjugation to hyaluronan widens therapeutic indications for ovarian cancer [PDF]
, 2015 Management of ovarian cancer still requires improvements in therapeutic options. A drug delivery strategy was tested that allows specific targeting of tumor cells in combination with a controlled release of a cytotoxic molecule. To this aim, the efficacy
Campisi, Monica +8 more
core +2 more sources
Hyaluronan in limb morphogenesis
Developmental Biology, 2007 Hyaluronan (HA) is a large glycosaminoglycan that is not only a structural component of extracellular matrices, but also interacts with cell surface receptors to promote cell proliferation, migration, and intracellular signaling. HA is a major component of the extracellular matrix of the distal subapical mesenchymal cells of the developing limb bud ...
Bryan P. Toole +3 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source