Results 71 to 80 of about 58,192 (295)

The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan. [PDF]

The Journal of cell biology, 1992
The hyaluronan receptor belongs to the polymorphic family of CD44 glycoproteins, which have been implicated in a variety of cellular functions including adhesion to hyaluronan and collagen, the binding of lymphocytes to high endothelial cells during extravasation, and conferring metastatic potential to carcinoma cells.
Charles B. Underhill, H. A. Nguyen, Martine Culty   +2 more
openaire   +3 more sources

Printing and Rerouting of Elastic and Protease Responsive Shape Memory Hydrogel Filaments

Advanced Healthcare Materials, EarlyView.
A biofabrication strategy, Rerouting of Free‐Floating Suspended Hydrogel Filaments (REFRESH), is developed enabling the printing of highly elastic, reconfigurable protease‐responsive hydrogel filaments with shape memory properties. The filaments can be manually braided, knotted, and rerouted to create intricate cell‐laden 3D architectures, expanding ...
Philip Lifwergren, Viktoria Schoen, Sajjad Naeimipour, Lalit Khare, Anna Wunder, Hanna Blom, Jose G. Martinez, Pierfrancesco Pagella, Anders Fridberger, Johan Junker, Daniel Aili   +10 more
wiley   +1 more source

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium.

Journal of the American Society of Nephrology, 2019
BACKGROUND A glycocalyx envelope consisting of proteoglycans and adhering proteins covers endothelial cells, both the luminal and abluminal surface. We previously demonstrated that short-term loss of integrity of the luminal glycocalyx layer resulted in ...
B. M. van den Berg, Gangqi Wang, Margien G. S. Boels, M. C. Avramut, Erik Jansen, Wendy M. P. J. Sol, F. Lebrin, Anton Jan van Zonneveld, E. D. de Koning, H. Vink, H. Gröne, P. Carmeliet, J. van der Vlag, Ton J. Rabelink   +13 more
semanticscholar   +1 more source

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

Advanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu, Rockie Haiyao Ding, Zixuan Zhao, Clara Yieh Lin Chong, Ruochii You, Hengjia Zhou, Dong Hua Seah, Wei Qiang Leow, Hong Kit Lim, Sukanya Shyamasundar, Kanishka Fernando, Fathima Farzana Kuthubudeen, Gillian Ng, Chor Yong Tay, Narayanan Gopalakrishna Iyer, Chin‐Ann Johnny Ong, Eliza Li Shan Fong   +16 more
wiley   +1 more source

Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells

JCI Insight, 2020
Successful implantation is associated with a unique spatial pattern of vascular remodeling, characterized by profound peripheral neovascularization surrounding a periembryo avascular niche.
Ron Hadas, Eran Gershon, Aviad Cohen, Ofir Atrakchi, Shlomi Lazar, Ofra Golani, Bareket Dassa, Michal Elbaz, Gadi Cohen, Raya Eilam, Nava Dekel, Michal Neeman   +11 more
doaj   +1 more source

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis

ACS Nano, 2017
Hyaluronan is a biologically active polymer, which can be formulated into nanoparticles. In our study, we aimed to probe atherosclerosis-associated inflammation by using hyaluronan nanoparticles and to determine whether they can ameliorate ...
Thijs J. Beldman, Max L. Senders, Amr Alaarg, C. Pérez-Medina, Jun Tang, Yiming Zhao, F. Fay, Jacqueline Deichmöller, B. Born, Emilie C B Desclos, N. N. van der Wel, R. Hoebe, F. Kohen, Elena Kartvelishvily, M. Neeman, T. Reiner, C. Calcagno, Z. Fayad, M. D. de Winther, E. Lutgens, W. Mulder, E. Kluza   +21 more
semanticscholar   +1 more source

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

SPERM SELECTION WITH HYALURONAN AND BLASTOCYST DEVELOPMENT AFTER ICSI

Zdravniški Vestnik, 2018
Background. Selection of mature sperm for intracytoplasmic sperm injection (ICSI) has recently been made possible by hyaluronan, a naturally occurring substance found in the cumulus cells.
Lili Bačer Kermavner, Irma Virant Klun, Eda Vrtačnik Bokal, Tomaž Tomaževič, Helena Meden Vrtovec   +4 more
doaj   +1 more source

Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study

Intensive Care Medicine Experimental, 2021
Background Plasma hyaluronan concentrations are increased during sepsis but underlying mechanisms leading to high plasma hyaluronan concentration are poorly understood.
Jaap van der Heijden, Constantinos Kolliopoulos, Paul Skorup, Marko Sallisalmi, Paraskevi Heldin, Michael Hultström, Jyrki Tenhunen   +6 more
doaj   +1 more source

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source