The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li +5 more
wiley +1 more source
Nanotechnology‐Enhanced Approaches for Early Cancer Diagnosis
Conventional MRI and PET provide limited sensitivity and contrast for precise brain lesion detection. In contrast, radiolabeled nanoparticlebased PET imaging enables enhanced signal specificity and sensitivity. By integrating multifunctional nanoprobes, this platform improves multimodal imaging performance, allowing more accurate visualization of ...
Jongmoo Lee +5 more
wiley +1 more source
Role of lymphatic endothelium specific hyaluronan receptor 1 in virus infection and associated diseases [PDF]
Lu Dai, Zhiqiang Qin
openalex +1 more source
Toll-like Receptor 2 (TLR2), Transforming Growth Factor-β, Hyaluronan (HA), and Receptor for HA-mediated Motility (RHAMM) Are Required for Surfactant Protein A-stimulated Macrophage Chemotaxis [PDF]
Joseph P. Foley +8 more
openalex +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
Intestinal Ischemia/Reperfusion Injury Influences Hyaluronan Homeostasis in the Rat Brain. [PDF]
Bosi A +14 more
europepmc +1 more source
Hyaluronan-dependent motility of B cells and leukemic plasma cells in blood, but not of bone marrow plasma cells, in multiple myeloma: alternate use of receptor for hyaluronan-mediated motility (RHAMM) and CD44 [PDF]
A Masellis-Smith +4 more
openalex +1 more source
ABSTRACT Shedding of the endothelial glycocalyx may be a pathophysiological mechanism in septic shock, to which intravenous (IV) fluid therapy may contribute. We aimed to investigate the effects of restrictive versus standard IV fluid therapy on glycocalyx shedding in adult intensive care unit (ICU) patients with septic shock.
Jens Christensen +13 more
wiley +1 more source
Hyaluronic Acid in Liver Fibrosis: Role in Inflammation, Tissue Remodeling, and Disease Progression. [PDF]
Rojano-Alfonso C +5 more
europepmc +1 more source
We report the development and application of a mouse ovarian somatic organoid model to elucidate a fundamental new understanding of the cell biology of the aging ovarian microenvironment. ABSTRACT Ovarian somatic cells are essential for reproductive function, but no existing ex vivo models recapitulate the cellular heterogeneity or interactions within ...
Shweta S. Dipali +10 more
wiley +1 more source

