Results 191 to 200 of about 2,309,824 (325)

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Extracellular Matrix Signaling Cues: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 8, August 2025.
Targeting ECM dysregulation: therapeutic strategies for disease intervention. Dysregulated ECM composition and biomechanics contribute to disease pathogenesis in cancer and fibrotic disorders. Physical modulation: Nanomedicine‐based strategies tune ECM physical properties (e.g., density, stiffness) to enhance drug penetration and therapeutic efficacy ...
Tian Zhao, Ye Huang, Jingfei Zhu, Yujie Qin, Hao Wu, Jiaxuan Yu, Qianwen Zhai, Shun Li, Xiang Qin, Dengfeng Wang, Tingting Li, Yiyao Liu   +11 more
wiley   +1 more source

Can the choice of artificial tears harm patients? A narrative review with an overview of the Nordic market

Acta Ophthalmologica, Volume 103, Issue 5, Page 586-608, August 2025.
Abstract Purpose To provide an overview of artificial tears marketed in the following Nordic countries: Denmark, Finland, Norway, Iceland and Sweden. Furthermore, this review aimed to highlight the different preservatives and other constituents found in artificial tears in the Nordic market, focussing on adverse effects.
K. N. Mikha, C. E. Ø. Rasmussen, S. N. G. Ahrensberg, J. Freiberg, R. A. Wozniak, U. M. K. Alnoor, F. Fineide, T. P. Utheim, S. Heegaard, M. Kolko   +9 more
wiley   +1 more source

Inflammation-induced Uptake and Degradation of the Lymphatic Endothelial Hyaluronan Receptor LYVE-1 [PDF]

, 2007
Louise A. Johnson, Remko Prevo, Steven Clasper, David G. Jackson   +3 more
openalex   +1 more source

Low Molecular Weight Hyaluronan Inhibits Lung Epithelial Ion Channels by Activating the Calcium-Sensing Receptor [PDF]

, 2022
Ahmed Lazrak, Weifeng Song, Zhihong Yu, Shaoyan Zhang, Anoma Nellore, Charles W. Hoopes, Bradford A. Woodworth, Sadis Matalon   +7 more
openalex   +1 more source

Antitumor Activities by a Humanized Cancer‐Specific Anti‐Podoplanin Monoclonal Antibody humPMab‐117 Against Human Tumors

Cancer Science, Volume 116, Issue 8, Page 2232-2242, August 2025.
A humanized cancer‐specific anti‐podoplanin monoclonal antibody humPMab‐117 exerts antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against human tumor cells. In the xenograft tumor models, humPMab‐117 demonstrated strong antitumor efficacy.
Tomohiro Tanaka, Hiroyuki Suzuki, Tomokazu Ohishi, Manabu Kawada, Mika K. Kaneko, Yukinari Kato   +5 more
wiley   +1 more source

Crohn’s Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan FragmentsSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Crohn’s Disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Fibrosis, a serious complication of CD, occurs when activated intestinal fibroblasts deposit excessive amounts of extracellular matrix (ECM) in ...
Artin Soroosh, Sami Albeiroti, Gail A. West, Belinda Willard, Claudio Fiocchi, Carol A. de la Motte   +5 more
doaj  

Faculty Opinions recommendation of Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

, 2002
Betty P. Tsao
openalex   +2 more sources

The Cytoplasmic Domain of the Hyaluronan Receptor for Endocytosis (HARE) Contains Multiple Endocytic Motifs Targeting Coated Pit-mediated Internalization [PDF]

, 2008
Madhu Pandey, Edward N. Harris, Janet A. Weigel, Paul H. Weigel   +3 more
openalex   +1 more source

Hyaluronan Accumulation Is Elevated in Cultures of Low Density Lipoprotein Receptor-deficient Cells and Is Altered by Manipulation of Cell Cholesterol Content [PDF]

, 2008
Sana W. Sakr, Susan Potter‐Perigo, Michael G. Kinsella, Pamela Y. Johnson, Kathleen R. Braun, Yann Gouëffic, Michael E. Rosenfeld, Thomas N. Wight   +7 more
openalex   +1 more source