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The fascial-interstitial system and the sanjiao-mocou system: an analogy-based hypothesis for the anatomical basis of meridian pathways. [PDF]
Front PhysiolXia Y, Jia Y, Qu H, Wei Q, Yan L, Li X.
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Platelet Hyaluronan Synthase 3 Regulates Thrombin Signaling and Adhesion to Fibrinogen Under Venous Shear. [PDF]
Proteoglycan ResQueisser KA +5 more
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Hyaluronan-binding proteins and receptors
Advanced Drug Delivery Reviews, 1991Abstract Hyaluranon is a glycosaminoglycan implicated in development, repair and disease processes. It appears to regulate these processes, in part, by interacting with specific binding proteins. These proteins can be conveniently divided into those that are primarily extracellular, including aggrecan, link protein(s), versican, hyaluronection or ...
Eva A Turley
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Hyaluronan and its receptors in mucoepidermoid carcinoma
Head and Neck, 2006Hyaluronan (HA) is a prominent extracellular matrix component undergoing continuous production and degradation. Increased HA levels have been described in a variety of tumors. The objective of this study was to examine the staining patterns of HA and two of its associated receptors (CD44 and HARE) in relation to the metastatic potential of ...
Richard O Wein +2 more
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Hyaluronan: Biosynthesis and signaling
Biochimica Et Biophysica Acta - General Subjects, 2014 Background Hyaluronan is a critical component of extracellular matrix with several different roles. Besides the contribution to the tissue hydration, mechanical properties and correct architecture, hyaluronan plays important biological functions ...
Davide Vigetti +2 more
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The International Journal of Biochemistry & Cell Biology, 2002
CD44 is a widely expressed cell surface hyaluronan receptor which plays a key role in mediating cell migration. A number of recent papers demonstrating an interplay between CD44 and matrix metalloproteinases (MMPs) have shed important insights into the molecular mechanisms underlying these events.
Clare M, Isacke, Helen, Yarwood
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CD44 is a widely expressed cell surface hyaluronan receptor which plays a key role in mediating cell migration. A number of recent papers demonstrating an interplay between CD44 and matrix metalloproteinases (MMPs) have shed important insights into the molecular mechanisms underlying these events.
Clare M, Isacke, Helen, Yarwood
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Internalization of the Hyaluronan Receptor CD44 by Chondrocytes
Experimental Cell Research, 1999Chondrocytes express CD44 as a primary receptor for the matrix macromolecule hyaluronan. Hyaluronan is responsible for the retention and organization of proteoglycan within cartilage, and hyaluronan-chondrocyte interactions are important for the assembly and maintenance of the cartilage matrix.
D J, Aguiar, W, Knudson, C B, Knudson
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Receptors for Hyaluronan on Corneal Endothelial Cells
Experimental Eye Research, 1994Previous investigations suggest that the corneal endothelium has specific binding sites for hyaluronan (HYA). In the present study, biochemical and immunological techniques were used to characterize these binding sites and to compare them with the liver endothelial cell (LEC) HYA receptor.
N, Forsberg +4 more
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Cellular uptake and internalization of hyaluronan-based doxorubicin and cisplatin conjugates [PDF]
Journal of Drug Targeting, 2014 Background Hyaluronan (HA) is a ligand for the CD44 receptor which is crucial to cancer cell proliferation and metastasis. High levels of CD44 expression in many cancers have encouraged the development of HA-based carriers for anti-cancer therapeutics.
Shuang Cai +2 more
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