Results 81 to 90 of about 280,681 (213)

Comparative Studies on the Structure and Biological Activities of Two New Polysaccharides From Tricholoma flavovirens (TF‐P) and Trametes versicolor (TV‐P)

Food Frontiers, EarlyView.
Two water‐soluble polysaccharides were isolated and purified from Tricholoma flavovirens (TF‐P) and Trametes versicolor (TV‐P), respectively. The structures of the two polysaccharides were identified by combining GPC, FT‐IR, HPLC, GC–MS, and NMR, and the structure–activity relationship has also been studied using immune cells and tumor cells. TV‐P with
Zheng‐Ao Sun, Nihui Zhao, Langlin Zheng, Feng Pan, Xiang Ding, Yiling Hou   +5 more
wiley   +1 more source

Salicylate suppresses the oncogenic hyaluronan network in metastatic breast cancer cells

Matrix Biology Plus, 2020
The oncogenic role of hyaluronan in several aspects of tumor biology has been well established. Recent studies by us and others suggest that inhibition of hyaluronan synthesis could represent an emerging therapeutic approach with significant clinical ...
Theodoros T. Karalis, Athanasios Chatzopoulos, Aikaterini Kondyli, Alexios J. Aletras, Nikos K. Karamanos, Paraskevi Heldin, Spyros S. Skandalis   +6 more
doaj  

Mediators of Inflammation and Their Effect on Resident Renal Cells: Implications in Lupus Nephritis [PDF]

, 2013
published_or_final_versio
Chan, DTM, Cheung, KF, Yung, SSY, Zhang, Q   +3 more
core   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

Ibrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis   +5 more
wiley   +1 more source

The Control and Importance of Hyaluronan Synthase Expression in Palatogenesis

Frontiers in Physiology, 2013
Development of the lip and palate involves a complex series of events that requires the close co-ordination of cell migration, growth, differentiation and apoptosis.
Jennifer eGalloway, Sarah eJones, Peter eMossey, Ian eEllis   +3 more
doaj   +1 more source

Expression of invasion-related extracellular matrix molecules in human glioblastoma versus intracerebral lung adenocarcinoma metastasis [PDF]

, 2010
Tumor cell invasion into the surrounding brain tissue is mainly responsible for the failure of radical surgical resection, with tumor recurrence in the form of microdisseminated disease.
Bognár, L., Hanzély, Z., Hutóczki, G., Kenyeres, A., Klekner, A., Mikó, E., Petrás, M., Scholtz, B., Tóth, J., Varga, I., Zahuczky, G.   +10 more
core   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Hyaluronan is crucial for stem cell differentiation into smooth muscle lineage [PDF]

, 2016
Deciphering the extracellular signals that regulate SMC differentiation from stem cells is vital to further our understanding of the pathogenesis of vascular disease and for development of cell-based therapies and tissue engineering.
Abhold, Bourguignon, Bourguignon, Bourguignon, Brecht, Brizzi, Burdon, Calabro, Chen, Chen, Choudhary, Chung, Clarkin, Cyphert, Eggli, Evanko, Evanko, Evans, Ferreira, Gerecht, Itano, Itano, Itano, Itano, Ito, Kakizaki, Kashima, Keller, Lam, Legg, Li, Liu, Liu, Marquez, Martin, Meran, Moyer, Nilsson, Pasonen-Seppanen, Peattie, Pilarski, Qu, Schraufstatter, Shukla, Simpson, Simpson, Sinha, Solis, Spicer, Spicer, Spicer, Tammi, Tang, Toole, Watt, Weigel, Xiao, Zeng, Zoltan-Jones, Zou   +59 more
core   +1 more source

Oligodendrocyte Precursor Cells in Demyelination Repair: Mechanisms, Crosstalk, and Therapeutic Frontiers

Medicine Bulletin, EarlyView.
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao, Mengdi Guo, Kehan Chen, Mei‐Ling Jiang, Lin‐ming Zhang, Lorenzo Di Cesare Mannelli, Cun‐jin Zhang   +6 more
wiley   +1 more source

SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network

EBioMedicine, 2022
Summary: Background: Since late 2019, SARS-CoV-2 infection has resulted in COVID-19 accompanied by diverse clinical manifestations. However, the underlying mechanism of how SARS-CoV-2 interacts with host and develops multiple symptoms is largely ...
Wei Li, Shuai Yang, Peng Xu, Dapeng Zhang, Ying Tong, Lu Chen, Ben Jia, Ang Li, Cheng Lian, Daoping Ru, Baolong Zhang, Mengxing Liu, Cancan Chen, Weihui Fu, Songhua Yuan, Chenjian Gu, Lu Wang, Wenxuan Li, Ying Liang, Zhicong Yang, Xiaoguang Ren, Shaoxuan Wang, Xiaoyan Zhang, Yuanlin Song, Youhua Xie, Hongzhou Lu, Jianqing Xu, Hailin Wang, Wenqiang Yu   +28 more
doaj