Results 141 to 150 of about 19,597 (211)

Biglycan : a multivalent proteoglycan providing structure and signals [PDF]

, 2013
Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Năstase, Mădălina-Viviana, Schäfer, Liliana, Young, Marian F.   +2 more
core  

Hyaluronan synthase 2 (HAS2); hyaluronidase 2 (HYAL2) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Mycosporine-like amino acids stimulate hyaluronan secretion by up-regulating hyaluronan synthase 2 via activation of the p38/MSK1/CREB/c-Fos/AP-1 axis. [PDF]

J Biol Chem, 2020
Terazawa S, Nakano M, Yamamoto A, Imokawa G.   +3 more
europepmc   +1 more source

Targeting hyaluronan synthesis enhances the therapeutic effectiveness of biologics in inflammatory bowel disease

JCI Insight
Although biologics have been revolutionizing the treatment of inflammatory bowel diseases (IBD) over the past decade, a significant number of patients still fail to benefit from these drugs.
Peng Xiao, Zhehang Chen, Xuechun Cai, Wenhao Xia, Xia Liu, Zhangfa Song, Huijuan Wang, Yuening Zhao, Youling Huang, Yu Zhang, Ke Guo, Haotian Chen, Rongbei Liu, Changcheng Meng, Yanfei Fang, Yunkun Lu, Qian Cao   +16 more
doaj   +1 more source

Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism. [PDF]

J Biol Chem, 2019
Terabe K, Ohashi Y, Tsuchiya S, Ishizuka S, Knudson CB, Knudson W.   +5 more
europepmc   +1 more source

Faculty Opinions recommendation of Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2021
Christopher Chen, Allison Drain
openaire   +2 more sources

4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression [PDF]

, 2014

core   +1 more source

Correction: Li et al. Genetic Deficiency of Hyaluronan Synthase 2 in the Developing Limb Mesenchyme Impairs Postnatal Synovial Joint Formation. Biomedicines 2025, 13, 1324. [PDF]

Biomedicines
Li Y, Tress A, Maye P, Edwards K, Findletar A, Dyment NA, Yamaguchi Y, Rowe DW, Le-Chan G, Chan SSK, Lo KW.   +10 more
europepmc   +1 more source

Hyaluronan network remodeling by ZEB1 and ITIH2 enhances the motility and invasiveness of cancer cells

The Journal of Clinical Investigation
Hyaluronan (HA) in the extracellular matrix promotes epithelial-mesenchymal transition (EMT) and metastasis; however, the mechanism by which the HA network constructed by cancer cells regulates cancer progression and metastasis in the tumor ...
Sieun Lee, Jihye Park, Seongran Cho, Eun Ju Kim, Seonyeong Oh, Younseo Lee, Sungsoo Park, Keunsoo Kang, Dong Hoon Shin, Song Yi Ko, Jonathan M. Kurie, Young-Ho Ahn   +11 more
doaj   +1 more source

Carnosine and Retinol Synergistically Inhibit UVB-Induced PGE₂ Synthesis in Human Keratinocytes through the Up-Regulation of Hyaluronan Synthase 2. [PDF]

Biomol Ther (Seoul)
Park IG, Jin SH, An S, Ki MW, Park WS, Kim HJ, Na Y, Noh M.   +7 more
europepmc   +1 more source