Results 121 to 130 of about 10,590 (199)
Fibroblasts as key effectors of acupuncture in treatment of rheumatoid arthritis
Frontiers in ImmunologyRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, cartilage degradation, and bone erosion. The diseases also involves pathological changes in the surrounding fascial tissues that lead to persistent pain ...
Shi-Wei Tu +35 more
doaj +1 more source
Expression of hyaluronan synthases and hyaluronidases in the MG63 osteoblast cell line
, 2006 The expression of hyaluronan synthases (1, 2 and 3) and hyaluronidases (1, 2, 3, 4 and PH20) was examined in the MG63 osteoblast cell line induced to mineralize in vitro and compared to the rate of glycosaminoglycan production.
Adams, J., Byers, S., Sander, G.
core +1 more source
Hyaluronan: Biosynthesis and signaling
, 2014 Background Hyaluronan is a critical component of extracellular matrix with several different roles. Besides the contribution to the tissue hydration, mechanical properties and correct architecture, hyaluronan plays important biological functions ...
Manuela Viola +11 more
core +1 more source
, 2018 Introduction: Lung cancer is the result of a multistep accumulation of genetic and/or epigenetic alterations; therefore, a better understanding of the molecular mechanism by which these alterations affect lung cancer pathogenesis would provide new ...
de Sa, Vanessa Karen, Sr., +4 more
core +1 more source
Emodin regulates cell cycle of non-small lung cancer (NSCLC) cells through hyaluronan synthase 2 (HA2)-HA-CD44/receptor for hyaluronic acid-mediated motility (RHAMM) interaction-dependent signaling pathway. [PDF]
Cancer Cell Int, 2021 Li M, Jin S, Cao Y, Xu J, Zhu S, Li Z.
europepmc +1 more source
Hyaluronan synthase 2 is an adverse prognostic marker in androgen receptor-negative breast cancer
, 2016 Aims The important role of hyaluronan synthase 2 (HAS2), an isozyme responsible for hyaluronan synthesis, in cancer has been increasingly recognised. However, only a few studies with inconsistent results have been reported in breast cancers. With a large
Cheung, Sai-Yin +6 more
core +1 more source
Efficient TGFβ-induced epithelial–mesenchymal transition depends on hyaluronan synthase HAS2
, 2013 Epithelial-mesenchymal transition (EMT) is a developmental program, which can be adopted by cancer cells to increase their migration and ability to form metastases. Transforming growth factor β (TGFβ) is a well-studied inducer of EMT. We demonstrate that
B Bernert +11 more
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Synthesis of heparosan oligosaccharides by Pasteurella multocida PmHS2 single-action transferases
, 2012 Pasteurella multocida heparosan synthase PmHS2 is a dual action glycosyltransferase that catalyzes the polymerization of heparosan polymers in a non-processive manner.
Eggink, G. +4 more
core +1 more source