Results 51 to 60 of about 5,143 (259)

In Vitro and Ex Vivo Mechanistic Understanding and Clinical Evidence of a Novel Anti-Wrinkle Technology in Single-Arm, Monocentric, Open-Label Observational Studies

Cosmetics, 2022
Skin aging is a biological process leading to visible skin alterations. The mechanism of action, clinical efficacy and tolerance of a novel anti-wrinkle technology were evaluated in two skin care products formulated for different skin types.
Vinay Bhardwaj, Jin Namkoong, Océane Tartar, Isabel Diaz, Junhong Mao, Joanna Wu   +5 more
doaj   +1 more source

Influence of hyaluronan on endometrial receptivity and embryo attachment in sheep [PDF]

, 2017
An increasing number of reports suggests a role of hyaluronan (HA) in female reproduction and interest in its application in assisted reproduction is rising.
Fouladi-Nashta, A A, Ghafari, F, Marei, W F A, Mohey-Elsaeed, O, Raheem, K A, Wathes, D C   +5 more
core   +3 more sources

Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema

Disease Models & Mechanisms, 2019
Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 years.
Scott D. Collum, Jose G. Molina, Ankit Hanmandlu, Weizhen Bi, Mesias Pedroza, Tinne C. J. Mertens, Nancy Wareing, Wang Wei, Cory Wilson, Wenchao Sun, Jayakumar Rajadas, Paul L. Bollyky, Kemly M. Philip, Dewei Ren, Rajarajan A. Thandavarayan, Brian A. Bruckner, Yang Xia, Michael R. Blackburn, Harry Karmouty-Quintana   +18 more
doaj   +1 more source

Cell density dependent stimulation of PAI-1 and hyaluronan synthesis by TGF-[béta] in orbital fibroblasts [PDF]

, 2018
L
Berta, Eszter, Erdei, Annamária, Galgóczi, Erika, Gazdag, Annamária, Győry, Ferenc, Jeney, Florence, Katkó, Mónika, M. Nagy, Domonkos, Nagy, Endre V., Steiber, Zita, Ujhelyi, Bernadett   +10 more
core   +1 more source

HAS2 (hyaluronan synthase 2) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on HAS2 (hyaluronan synthase 2), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +2 more sources

Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms [PDF]

, 2016
Hyaluronic acid, or HA, is a rigid and linear biopolymer belonging to the class of the glycosaminoglycans, and composed of repeating units of the monosaccharides glucuronic acid and N-acetylglucosamine.
Carvalho, Lucas Silva, Gomes, Antônio Milton Vieira, Magalhães, Beatriz Simas, Oliveira, Juliana Davies de, Parachin, Nádia Skorupa, Queiroz, Lúcio Rezende   +5 more
core   +2 more sources

Cancer Microenvironment and Inflammation: Role of Hyaluronan [PDF]

, 2015
The role of inflammation in the development of cancer was described as early as 19th century. Abundant evidence supports the preposition that various cancers are triggered by infection and chronic inflammatory disease whereas, evading immune destruction ...
Aikaterini Berdiaki, Aristidis Tsatsakis, Dragana Nikitovic, George N. Tzanakakis, Maria Tzardi   +4 more
core   +2 more sources

Hyaluronan synthase 2 expressed by cancer-associated fibroblasts promotes oral cancer invasion

Journal of Experimental & Clinical Cancer Research, 2016
Background Hyaluronan synthases (HAS) control the biosynthesis of hyaluronan (HA) and critically modulate the tumor microenviroment. Cancer-associated fibroblasts (CAFs) affect the progression of a tumor by remolding the matrix.
Ziwen Zhang, Detao Tao, Ping Zhang, Xue Liu, Yuchao Zhang, Jie Cheng, Hua Yuan, Laikui Liu, Hongbing Jiang   +8 more
doaj   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

Nanozyme‐Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy

Advanced Science, EarlyView.
A nanozyme–integrated hydrogel (PTC‐MP) exhibiting with mild photothermal effects is constructed, and a “3R” (restrain‐restore‐reinforce) strategy is proposed for diabetic osteoarthritis (DOA) treatment based on advanced glycation end products (AGEs) targeting.
Rui Chen, Yanguo Su, Guiyuan Zhao, Jiaojiao Tao, Qijie Diao, Guangli Xiang, Tianze Jiang, Lu Han, Xia Zhao   +8 more
wiley   +1 more source