Results 61 to 70 of about 5,143 (259)

Equine Endometrosis Pathological Features: Are They Dependent on NF-κB Signaling Pathway?

Animals, 2021
Endometrosis is an important mares’ disease which considerably decreases their fertility. As classic endometrial classification methods might be insufficient for tissue pathological evaluation, further categorization into active/inactive and destructive ...
Tomasz Jasiński, Łukasz Zdrojkowski, Ewa Kautz, Edyta Juszczuk-Kubiak, Graça Ferreira-Dias, Małgorzata Domino   +5 more
doaj   +1 more source

No jacket required – new fungal lineage defies dress code [PDF]

, 2012
Analyses of environmental DNAs have provided tantalizing evidence for “rozellida” or “cryptomycota”, a clade of mostly undescribed and deeply diverging aquatic fungi. Here, we put cryptomycota into perspective through consideration of Rozella , the only
Abramczyk, Amaral-Zettler, Amend, Aronson, Barr, Bass, Bland, Bowman, Bulawa, Choquer, Dawson, Edgar, Fierer, Fortin, Franzen, Frohlich-Nowoisky, Guerriero, Held, Held, Held, Held, Hibbett, Hibbett, Humber, Itoh, James, Jing, Jones, Jones, Jumpponen, Karling, Keeling, Kim, Kirk, Lacey, Lara, Le Calvez, Leal-Morales, Lefranc, Lefèvre, Lefèvre, Lehninger, Lenardon, Lepere, Lesaulnier, Lopez, Lutzoni, Mangot, Marchler-Bauer, Marshall, Mohamed, Munro, Nagahama, Nagano, Not, O'Brien, Pendland, Porter, Porter, Powell, Qu, Roncero, Ruiz-Herrera, Ruiz-Herrera, Ruiz-Trillo, Schadt, Sekimoto, Shanor, Slapeta, Smith, Sparrow, Stajich, Steenkamp, Stoeck, Takishita, Treitschke, Tsuizaki, van Hannen, Vandenkoornhuyse, Whisler, Wolf   +80 more
core   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Divergent temporal expression of hyaluronan metabolizing enzymes and receptors with craniotomy vs. controlled cortical impact injury in rat brain: A pilot study

Frontiers in Neurology, 2014
Traumatic brain injury triggers many secondary changes in tissue biology which ultimately determine the extent of injury and clinical outcome. Hyaluronan (hyaluronic acid, HA) is a protective cementing gel present in the intercellular spaces whose ...
Guoqiang eXing, Ming eRen, Ajay eVerma
doaj   +1 more source

Mediators of Inflammation and Their Effect on Resident Renal Cells: Implications in Lupus Nephritis [PDF]

, 2013
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Chan, DTM, Cheung, KF, Yung, SSY, Zhang, Q   +3 more
core   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells [PDF]

, 2013
Thickening of the vessel in response to high low density lipoprotein(s) (LDL) levels is a hallmark of atherosclerosis, characterized by increased hyaluronan (HA) deposition in the neointima.
Bartolini, B., De Luca, G., Deleonibus, S., Hascall, V.C., Karousou, E., Moretto, P., Passi, A., Sawamura, T., Vigetti, D., Viola, M., Wight, T.N.   +10 more
core   +1 more source

Hyaluronan Synthase Induction and Hyaluronan Accumulation in Mouse Epidermis Following Skin Injury [PDF]

Journal of Investigative Dermatology, 2005
Hyaluronan, a major extracellular matrix component in the epidermis, has been shown to control keratinocyte proliferation and differentiation in vitro. We assayed hyaluronan and hyaluronan synthases (has1-3) in mouse epidermis during fetal development, postnatal life, and trauma reaction in vivo. Hyaluronan increased in the epidermis when keratinocytes
Tammi, Raija, Pasonen-Seppänen, Sanna, Kolehmainen, Elina, Tammi, Markku   +3 more
openaire   +2 more sources

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke. [PDF]

, 2013
Focal stroke is a disabling disease with lifelong sensory, motor and cognitive impairments. Given the paucity of effective clinical treatments, basic scientists are developing novel options for protection of the affected brain and regeneration of lost ...
Carmichael, S Thomas, Moshayedi, Pouria
core   +1 more source