Results 61 to 70 of about 2,588 (196)
Equine Endometrosis Pathological Features: Are They Dependent on NF-κB Signaling Pathway?
Animals, 2021 Endometrosis is an important mares’ disease which considerably decreases their fertility. As classic endometrial classification methods might be insufficient for tissue pathological evaluation, further categorization into active/inactive and destructive ...
Tomasz Jasiński +5 more
doaj +1 more source
Food Frontiers, EarlyView.Two water‐soluble polysaccharides were isolated and purified from Tricholoma flavovirens (TF‐P) and Trametes versicolor (TV‐P), respectively. The structures of the two polysaccharides were identified by combining GPC, FT‐IR, HPLC, GC–MS, and NMR, and the structure–activity relationship has also been studied using immune cells and tumor cells. TV‐P with
Zheng‐Ao Sun +5 more
wiley +1 more source
Hyaluronan Biosynthesis by Class I Streptococcal Hyaluronan Synthases Occurs at the Reducing End [PDF]
Journal of Biological Chemistry, 2005 Previous studies reached different conclusions about whether class I hyaluronan synthases (HASs) elongate hyaluronic acid (HA) by addition to the reducing or the nonreducing end. Here we used two strategies to determine the direction of HA synthesis by purified class I HASs from Streptococcus equisimilis and Streptococcus pyogenes.
Christina A. Baron +5 more
openaire +3 more sources
Heliyon, 2023 Hyaluronic acid (HA) is a crucial component of the extracellular matrix, and its level of accumulation is related to the progression of various malignant tumors. In this study, a pan-cancer analysis of the three enzymes called hyaluronan synthases (HAS1,
Xunxia Bao +9 more
doaj
Ibrain, EarlyView.Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka +5 more
wiley +1 more source
Inhibition of hyaluronan synthesis reduces versican and fibronectin levels in trabecular meshwork cells. [PDF]
PLoS ONE, 2012 Hyaluronan (HA) is a major component of the extracellular matrix (ECM) and is synthesized by three HA synthases (HAS). Similarities between the HAS2 knockout mouse and the hdf mutant mouse, which has a mutation in the versican gene, suggest that HA and ...
Kate E Keller +4 more
doaj +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrometry Reviews, EarlyView.Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Medicine Bulletin, EarlyView.ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao +6 more
wiley +1 more source
In Vitro Anti-Photoaging and Skin Protective Effects of Licania macrocarpa Cuatrec Methanol Extract
Plants, 2022 The Licania genus has been used in the treatment of dysentery, diabetes, inflammation, and diarrhea in South America. Of these plants, the strong anti-inflammatory activity of Licania macrocarpa Cuatrec (Chrysobalanaceae) has been reported previously ...
Kon Kuk Shin +14 more
doaj +1 more source
Gut Microbiota as a Mediator Between Intestinal Fibrosis and Creeping Fat in Crohn's Disease
United European Gastroenterology Journal, EarlyView.ABSTRACT Intestinal stricture remains one of the most challenging complications in Crohn's disease, and its underlying mechanisms are poorly understood. Accumulating evidence suggests that gut microbiota is significantly altered in stenotic intestines and may play a key role in the development of fibrogenesis in Crohn's disease.
Caiguang Liu +14 more
wiley +1 more source