Results 71 to 80 of about 265,910 (261)
Hyaluronan Synthase Induction and Hyaluronan Accumulation in Mouse Epidermis Following Skin Injury [PDF]
Journal of Investigative Dermatology, 2005 Hyaluronan, a major extracellular matrix component in the epidermis, has been shown to control keratinocyte proliferation and differentiation in vitro. We assayed hyaluronan and hyaluronan synthases (has1-3) in mouse epidermis during fetal development, postnatal life, and trauma reaction in vivo. Hyaluronan increased in the epidermis when keratinocytes
Elina Kolehmainen +3 more
openaire +3 more sources
Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells [PDF]
, 2013 Thickening of the vessel in response to high low density lipoprotein(s) (LDL) levels is a hallmark of atherosclerosis, characterized by increased hyaluronan (HA) deposition in the neointima.
Bartolini, B. +10 more
core +1 more source
Hyaluronan synthase 2 expressed by cancer-associated fibroblasts promotes oral cancer invasion
Journal of Experimental & Clinical Cancer Research, 2016 Background Hyaluronan synthases (HAS) control the biosynthesis of hyaluronan (HA) and critically modulate the tumor microenviroment. Cancer-associated fibroblasts (CAFs) affect the progression of a tumor by remolding the matrix.
Ziwen Zhang +8 more
doaj +1 more source
Matrix Biology Plus, 2021 In the extracellular matrix (ECM), the glycosaminoglycan (GAG) hyaluronan (HA) has different physiological roles favouring hydration, elasticity and cell survival.
Arianna Parnigoni +6 more
doaj
Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke. [PDF]
, 2013 Focal stroke is a disabling disease with lifelong sensory, motor and cognitive impairments. Given the paucity of effective clinical treatments, basic scientists are developing novel options for protection of the affected brain and regeneration of lost ...
Carmichael, S Thomas, Moshayedi, Pouria
core +1 more source
Equine Endometrosis Pathological Features: Are They Dependent on NF-κB Signaling Pathway?
Animals, 2021 Endometrosis is an important mares’ disease which considerably decreases their fertility. As classic endometrial classification methods might be insufficient for tissue pathological evaluation, further categorization into active/inactive and destructive ...
Tomasz Jasiński +5 more
doaj +1 more source
Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
Advanced NanoBiomed Research, EarlyView.This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou +4 more
wiley +1 more source
Functional Cloning of the cDNA for a Human Hyaluronan Synthase [PDF]
Journal of Biological Chemistry, 1996 Hyaluronan is a constituent of the extracellular matrix of connective tissue and is actively synthesized during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of hyaluronan are associated with inflammatory and degenerative arthropathies such as rheumatoid ...
Tadashi Yoshino +4 more
openaire +3 more sources
The use of human adipose-derived stem cells in the treatment of physiological and pathological vulvar dystrophies [PDF]
, 2016 “Vulvar dystrophy” is characterized by chronic alterations of vulvar trophism, occurring in both physiological (menopause) and pathological (lichen sclerosus, vulvar graft-versus-host disease) conditions.
CARELLA, SARA +4 more
core +4 more sources
Frontiers in Neurology, 2014 Traumatic brain injury triggers many secondary changes in tissue biology which ultimately determine the extent of injury and clinical outcome. Hyaluronan (hyaluronic acid, HA) is a protective cementing gel present in the intercellular spaces whose ...
Guoqiang eXing, Ming eRen, Ajay eVerma
doaj +1 more source