A novel hyaluronidase from brown spider (Loxosceles intermedia) venom (Dietrich's Hyaluronidase): from cloning to functional characterization. [PDF]
PLoS Neglected Tropical Diseases, 2013 Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. The venom contains several enzymatic toxins.
Valéria Pereira Ferrer +9 more
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Combination Hyaluronidase and Triamcinolone Acetonide Enzymatic Injections for Treatment of Ledderhose Disease: A Novel Technique and Case Series [PDF]
Clinics and PracticeBackground: Ledderhose Disease, or plantar fibromatosis, is a fibroproliferative disorder affecting the plantar fascia with limited effective treatment options.
Paul Carroll +5 more
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Therapeutic hyaluronidase to provide optimal aesthetic outcomes: A case report and call to action [PDF]
SAGE Open Medical Case ReportsWith hyaluronic acid injectable treatments becoming increasingly popular, more patients are presenting with pre-existing hyaluronic acid creating a poor cosmetic effect, requiring subsequent dissolving with hyaluronidase.
Jennifer Salsberg, Allison Sutton
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Treatment of [99mTc]Tc‐hydroxy‐diphosphonate ([99mTc]Tc‐HDP) extravasation using hyaluronidase [PDF]
Pharmacology Research & PerspectivesExtravasation of 99mTc‐labeled radiopharmaceuticals is generally considered to require no specific intervention. In the presented case, the use of hyaluronidase could have minimized the adverse effects resulting from such an extravasation.
Kevin R. Doornhof +3 more
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Isolation, Characterization, and Biological Activity of Phospholipase A2 (PLA2) and Hyaluronidase from Iranian Honey Bee Venom (Apis Mellifera meda) [PDF]
مجله بیوتکنولوژی کشاورزی, 2023 ObjectiveBee venom contains various enzymes such as hyaluronidase and phospholipase A2, which have medical and pharmaceutical applications. In several studies, the activity of phospholipase A2 and hyaluronidase has been reported in different bee species,
Mahmood Nazari +2 more
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Molecular, immunological, and biological characterization of Tityus serrulatus venom hyaluronidase: new insights into its role in envenomation. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND: Scorpionism is a public health problem in Brazil, and Tityus serrulatus (Ts) is primarily responsible for severe accidents. The main toxic components of Ts venom are low-molecular-weight neurotoxins; however, the venom also contains poorly ...
Carolina Campolina Rebello Horta +8 more
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Pharmaceutics, 2023 Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-promoting effect, which may motivate the diffusion and absorption of drugs. To verify the penetration osmotic effect of hyaluronidase in microneedles, 55 nm-size
Xiaoqing Miao +3 more
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Hyaluronidase: An overview of its properties, applications, and side effects
Archives of Plastic Surgery, 2020 Hyaluronidase, an enzyme that breaks down hyaluronic acid, has long been used to increase the absorption of drugs into tissue and to reduce tissue damage in cases of extravasation of a drug.
Hyunwook Jung
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Allergic reactions to hyaluronidase in pain management -A report of three cases- [PDF]
Korean Journal of Anesthesiology, 2011 Hyaluronidase has been gaining interest because it reduces tissue edema and fibrosis. Although rare, hyaluronidase has been shown to cause allergic reactions.
Tae Wan Kim +3 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Oleanolic acid (OA) is a natural cosmeceutical compound with various skin beneficial activities including inhibitory effect on hyaluronidase but the anti-hyaluronidase activity and mechanisms of action of its synthetic analogues remain unclear. Herein, a
Hao He +8 more
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