Results 61 to 70 of about 82,831 (293)

Hybrid excited claw pole generator with skewed and non-skewed permanent magnets

Open Physics, 2017
This article contains simulation results of the Hybrid Excited Claw Pole Generator with skewed and non-skewed permanent magnets on rotor. The experimental machine has claw poles on two rotor sections, between which an excitation control coil is located ...
Wardach Marcin
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

MOSAIC: A Scalable reconfigurable 2D array system for NDT [PDF]

, 2008
This paper documents the development of a scalable 2D array system, or Mosaic that can be targeted at a wide range of NDT applications by way of a reconfigurable tile that can be tessellated to form arrays of any size and shape.
Afroukh, F., Donald O. Thompson, L. Wang, D. R. S. Cumming, Dale E. Chimenti, J. Wallace, Wallace, J., Cumming, D.R.S., Wang, L., Cochran, S., Saillant, J.F., S. Triger, Saillant, J-F., S. Cochran, Triger, S., J. F. Saillant, F. Afroukh   +16 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The experimental evidence of a strong coupling regime in the hybrid Tamm plasmon-surface plasmon polariton mode

Nanophotonics, 2021
Total internal reflection ellipsometry was employed for the excitation and study of hybrid Tamm plasmon-surface plasmon polaritons mode. Simple optical methodology using optical filters to cut the part of incident light spectra was proposed.
Bužavaitė-Vertelienė Ernesta, Vertelis Vilius, Balevičius Zigmas   +2 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hybrid Excitation of the Axial Inductor Machine [PDF]

Latvian Journal of Physics and Technical Sciences, 2012
The paper considers the possibility to use permanent magnets in the rotor slots of axial inductor machine with the aim to create a hybrid excitation of such a machine − from the magnets and from the excitation winding which is placed between the stator cores.
S. Orlova, V. Pugachov, N. Levin
openaire   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source