Decoration of nanovesicles with pH (low) insertion peptide (pHLIP) for targeted delivery [PDF]
Acidity at surface of cancer cells is a hallmark of tumor microenvironments, which does not depend on tumor perfusion, thus it may serve as a general biomarker for targeting tumor cells.
Andreev O. A. +9 more
core +1 more source
New Vesicle−Polymer Hybrids: The Parachute Architecture
The influence of organized media on polymerization reactions results in many cases in interesting morphologies of the polymeric material. In the present study, vesicle bilayers were used as ordered medium for the free radical polymerization of styrene.
Jung, M. +7 more
openaire +2 more sources
Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production [PDF]
Although many recombinant proteins have been produced in seeds at high yields without adverse effects on the plant, endoplasmic reticulum (ER) stress and aberrant localization of endogenous or recombinant proteins have also been reported.
Arcalis, Elsa +13 more
core +2 more sources
A new type of Na+-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif [PDF]
: The anaerobic bacterium Fusobacterium nucleatum uses glutamate decarboxylation to generate a transmembrane gradient of Na+. Here, we demonstrate that this ion-motive force is directly coupled to ATP synthesis, via an F1Fo-ATP synthase with a novel Na ...
Faraldo-Gómez, José D. +8 more
core +3 more sources
In situ hybridization to detect DNA amplification in extracellular vesicles [PDF]
AbstractEVs have emerged as an important component in tumour initiation, progression and metastasis. Although notable progresses have been made, the detection of EV cargoes remain significantly challenging for researchers to practically use; faster and more convenient methods are required to validate the EV cargoes, especially as biomarkers.
Casadei, L. +11 more
openaire +3 more sources
The role of surface charge in the interaction of nanoparticles with model pulmonary surfactants [PDF]
Inhaled nanoparticles traveling through the airways are able to reach the respiratory zone of the lungs. In such event, the incoming particles first enter in contact with the liquid lining the alveolar epithelium, the pulmonary surfactant.
Berret, J. -F., Mousseau, F.
core +4 more sources
Monoubiquitin-dependent endocytosis of the Iron-Regulated Transporter 1 (IRT1) transporter controls iron uptake in plants [PDF]
Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1) high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow plants to tightly control the levels of IRT1, ensuring optimal absorption of ...
Barberon, Marie +6 more
core +3 more sources
Hybrid lipid/block copolymer vesicles display broad phase coexistence region [PDF]
The fluidity and polar environment of ~100 nm hybrid vesicles combining dipalmitoylphosphatidylcholine (DPPC) and poly(1,2-butadiene)-block-polyethylene oxide (PBd-PEO, average molecular weight 950 g/mol) were studied upon vesicle heating using the fluorescence spectroscopy techniques of DPH anisotropy and laurdan generalized polarization (GP).
Hamada, Naomi +2 more
openaire +4 more sources
Early endosomes, regarded as the main sorting station on endocytic pathway, are characterized by high frequency of homotypic fusions mediated by tethering protein EEA1.
Rimma Kamentseva +7 more
doaj +1 more source
Extracellular vesicles (EVs) have potential biomedical applications, particularly as a means of transport for therapeutic agents. There is a need for rapid and efficient EV‐liposome membrane fusion that maintains the integrity of hybrid EVs.
Raga Ishikawa +4 more
doaj +1 more source

