Results 41 to 50 of about 41,031 (146)
Extracellular Vesicle-Based Hybrid Systems for Advanced Drug Delivery [PDF]
Pharmaceutics, 2022 The continuous technological advancement of nanomedicine has enabled the development of novel vehicles for the effective delivery of therapeutic substances. Synthetic drug delivery systems are nano-sized carriers made from various materials that can be designed to deliver therapeutic cargoes to cells or tissues.
Rodríguez, Diego A., Vader, Pieter
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FEBS Open Bio, 2022 Extracellular vesicles (EVs) have potential biomedical applications, particularly as a means of transport for therapeutic agents. There is a need for rapid and efficient EV‐liposome membrane fusion that maintains the integrity of hybrid EVs.
Raga Ishikawa +4 more
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Mover is a homomeric phospho-protein present on synaptic vesicles.
PLoS ONE, 2013 With remarkably few exceptions, the molecules mediating synaptic vesicle exocytosis at active zones are structurally and functionally conserved between vertebrates and invertebrates. Mover was found in a yeast-2-hybrid assay using the vertebrate-specific
Saheeb Ahmed +9 more
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Hybrid Bacteria System with Nanomaterials for Tumor Therapy
Advanced NanoBiomed Research, 2023 Recently, bacteria‐mediated therapy has been widely applied for tumor treatments owing to some inherent features of bacteria. With further advancements in genetic engineering and nanotechnology, natural bacteria are endowed with extra capacities of ...
Qinyi Zhang, Xiaotu Ma, Xiao Zhao
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Flippase‐Mediated Hybrid Vesicle Division
Advanced MaterialsAbstract The assembly of synthetic systems with the ability for protein‐mediated division remains a challenge in bottom‐up synthetic biology. Here, the reconstitution of an active Drs2p–Cdc50p lipid flippase in polymer lipid hybrid vesicles (HVs) made from phospholipids and 1 or 2.5 mol% amphiphilic block ...
Paula De Dios Andres +5 more
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Vesicle and reaction-diffusion hybrid modeling with STEPS
Communications BiologyAbstract Vesicles carry out many essential functions within cells through the processes of endocytosis, exocytosis, and passive and active transport. This includes transporting and delivering molecules between different parts of the cell, and storing and releasing neurotransmitters in neurons.
Iain Hepburn +5 more
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Small StructuresBiological membranes orchestrate multistep chemistry creating microenvironments, enabling selective transport and separating redox reactions, principles that, when translated into artificial vesicles, can unlock powerful platforms for photocatalysis ...
Edelman José Espinoza‐Suárez +4 more
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Frontiers in Molecular Biosciences, 2023 Extracellular vesicles (EVs), including exosomes, with nanoscale sizes, biological origins, various functions, and unique lipid and protein compositions have been introduced as versatile tools for diagnostic and therapeutic medical applications. Numerous
Samaneh Ghadami, Kristen Dellinger
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Dendrimer Induced Bilayer Disintegration of Hybrid Vesicles
Journal of Oleo SciencePhysicochemical investigations on the inclusion of anionic polyamidoaminesuccinamic acid dendrimer, generation 5 (PAMAM-SA, G5) with positively charged hybrid vesicles (HCV), prepared using soylecithin, ion pair amphiphile (IPA), cholesterol and dihexadecyldimethylammonium bromide, were investigated by dynamic light scattering, transmission electron ...
Guha, Pritam +10 more
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Nature Communications, 2017 Extracellular vesicles (EV)-associated RNAs are serum biomarkers potentially exploitable for early cancer diagnosis. Here the authors develop a catalyzed hairpin DNA circuit within a cationic lipid-polymer hybrid nanoparticle that can detect low–level EV-
Jiaming Hu +5 more
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