Results 21 to 30 of about 41,031 (146)

Hybrid extracellular vesicles for drug delivery

Cancer Letters, 2023
Extracellular vesicles (EVs) are expected to serve as interesting drug delivery vectors as they may offer unique and new properties for drug delivery. Their natural origin, protein and nucleic acid composition, and intrinsic pleiotropic therapeutic effects could enable new possibilities in the field of drug delivery.
Ducrot, Coline, Loiseau, Stanislas, Wong, Christophe, Madec, Elise, Volatron, Jeanne, Piffoux, Max   +5 more
openaire   +2 more sources

Phytochemicals and Cancer Treatment: Cell-Derived and Biomimetic Vesicles as Promising Carriers

Pharmaceutics, 2023
The majority of anticancer agents currently used derive from natural sources: plants, frequently the ones employed in traditional medicines, are an abundant source of mono- and diterpenes, polyphenols, and alkaloids that exert antitumor activity through ...
Sara Baldassari, Alice Balboni, Giuliana Drava, Daniela Donghia, Paolo Canepa, Giorgia Ailuno, Gabriele Caviglioli   +6 more
doaj   +1 more source

In situ hybridization to detect DNA amplification in extracellular vesicles [PDF]

Journal of Extracellular Vesicles, 2022
AbstractEVs have emerged as an important component in tumour initiation, progression and metastasis. Although notable progresses have been made, the detection of EV cargoes remain significantly challenging for researchers to practically use; faster and more convenient methods are required to validate the EV cargoes, especially as biomarkers.
Casadei, L., Sarchet, P., de Faria, FCC, Calore, F., Nigita, G., Tahara, S., Cascione, L., Wabitsch, M., Hornicek, F.J., Grignol, V., Croce, C.M., Pollock, R.E.   +11 more
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Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life

Advanced Science, 2022
The construction of biomembranes that faithfully capture the properties and dynamic functions of cell membranes remains a challenge in the development of synthetic cells and their application.
Anna M. Wagner, Jonas Quandt, Dominik Söder, Manuela Garay‐Sarmiento, Anton Joseph, Vladislav S. Petrovskii, Lena Witzdam, Thomas Hammoor, Philipp Steitz, Tamás Haraszti, Igor I. Potemkin, Nina Yu. Kostina, Andreas Herrmann, Cesar Rodriguez‐Emmenegger   +13 more
doaj   +1 more source

Lipid-hybrid cell-derived biomimetic functional materials: A state-of-the-art multifunctional weapon against tumors

Materials Today Bio, 2023
Tumors are among the leading causes of death worldwide. Cell-derived biomimetic functional materials have shown great promise in the treatment of tumors. These materials are derived from cell membranes, extracellular vesicles and bacterial outer membrane
Wen-Shang Liu, Li-Li Wu, Cui-Min Chen, Hao Zheng, Jie Gao, Zheng-Mao Lu, Meng Li   +6 more
doaj   +1 more source

Membrane composition of polymer-lipid hybrid vesicles

Applied Materials Today, 2022
Hybrid vesicles (HVs) assembled from phospholipids and amphiphilic block copolymers (BCPs) are a more recent alternative to liposomes and polymersomes. We aim to change the properties of the HV membranes by varying the chemical composition of the hydrophobic block in the BCPs that have poly(carboxyethyl acrylate) (PCEA) as the hydrophilic part. To this
Brodszkij, Edit, Westensee, Isabella Nymann, Holleufer, Steffen Friis, Ade, Carina, Andres, Paula De Dios, Pedersen, Jan Skov, Städler, Brigitte   +6 more
openaire   +2 more sources

Neurosecretory vesicles can be hybrids of synaptic vesicles and secretory granules. [PDF]

Proceedings of the National Academy of Sciences, 1995
We have investigated the relationship of the so-called small dense core vesicle (SDCV), the major catecholamine-containing neurosecretory vesicle of sympathetic neurons, to synaptic vesicles containing classic neurotransmitters and secretory granules containing neuropeptides.
R, Bauerfeind, R, Jelinek, A, Hellwig, W B, Huttner   +3 more
openaire   +2 more sources

Cell membrane-derived vesicles for delivery of therapeutic agents

Acta Pharmaceutica Sinica B, 2021
Cell membranes have recently emerged as a new source of materials for molecular delivery systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles. Unlike synthetic lipid or polymeric nanoparticles, cell membrane-derived vesicles
Quoc-Viet Le, Jaiwoo Lee, Hobin Lee, Gayong Shim, Yu-Kyoung Oh   +4 more
doaj   +1 more source

Entropy-driven segregation and budding in hybrid vesicles of binary nanoparticle amphiphiles

Giant, 2020
Self-assembly of giant building blocks beyond conventional molecules offers tremendous opportunities for the fabrication of new-generation structural materials.
Chelsey Lamar, Yijing Liu, Chenglin Yi, Zhihong Nie   +3 more
doaj   +1 more source

Application of lipid nanovesicle drug delivery system in cancer immunotherapy

Journal of Nanobiotechnology, 2022
Immunotherapy has gradually emerged as the most promising anticancer therapy. In addition to conventional anti-PD-1/PD-L1 therapy, anti-CTLA-4 therapy, CAR-T therapy, etc., immunotherapy can also be induced by stimulating the maturation of immune cells ...
Yinan Ding, Luhong Wang, Han Li, Fengqin Miao, Zhiyuan Zhang, Chunmei Hu, Weiping Yu, Qiusha Tang, Guoliang Shao   +8 more
doaj   +1 more source