Polymer–Lipid Hybrid Vesicles and Their Interaction with HepG2 Cells
Small, 2020 AbstractPolymer–lipid hybrid vesicles are an emerging type of nano‐assemblies that show potential as artificial organelles among others. Phospholipids and poly(cholesteryl methacrylate)‐block‐poly(methionine methacryloyloxyethyl ester (METMA)—random–2‐carboxyethyl acrylate (CEA)) labeled with a Förster resonance energy transfer (FRET) reporter pair are
E Brodszkij +2 more
exaly +4 more sources
Hybrid Unilamellar Vesicles of Phospholipids and Block Copolymers with Crystalline Domains [PDF]
Polymers, 2020 Phospholipid (PL) membranes are ubiquitous in nature and their phase behavior has been extensively studied. Lipids assemble in a variety of structures and external stimuli can activate a quick switch between them. Amphiphilic block copolymers (BCPs) can self-organize in analogous structures but are mechanically more robust and transformations are ...
Cecilia Leal +2 more
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Engineered vesicles enhance oral antibiotic absorption in proximal small intestine and mitigate gut dysbiosis [PDF]
Nature CommunicationsOral antibiotics are a mainstay for treating bacterial infections, but unabsorbed portions can reach the caecum and colon, leading to gut dysbiosis. Herein, we engineer a biohybrid delivery system through the integration of milk extracellular vesicles ...
Yinglan Yu +8 more
doaj +2 more sources
Recent Advances on Extracellular Vesicles: A Natural Nanomaterial for Biomedical Application [PDF]
BiomimeticsExtracellular vesicles (EVs), naturally secreted by cells as nanoscale lipid bilayer structures, have become a research hotspot in biomedicine owing to their excellent biocompatibility, low immunogenicity, and inherent ability to cross biological ...
Fan Li +5 more
doaj +2 more sources
Size Enlargement Enabled Functional Profiling of Extracellular Vesicle at Single-Particle Level [PDF]
BiosensorsExtracellular vesicles (EVs) are promising biomarkers for liquid biopsy, but their clinical application is limited by intrinsic heterogeneity and the lack of methods capable of resolving functionally distinct EV subpopulations at the single-vesicle level.
Jia Yao +5 more
doaj +2 more sources
Recent Advancements in Polymer/Liposome Assembly for Drug Delivery: From Surface Modifications to Hybrid Vesicles [PDF]
Polymers, 2021 Francesco Milano +2 more
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Monitoring and modulating ion traffic in hybrid lipid/polymer vesicles
Colloids and Surfaces B: Biointerfaces, 2017 Controlling the traffic of molecules and ions across membranes is a critical feature in a number of biologically relevant processes and highly desirable for the development of technologies based on membrane materials. In this paper, ion transport behavior of hybrid lipid/polymer membranes was studied in the absence and presence of ion transfer agents ...
Komandoor Achyuthan +2 more
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Carbon Dots and Biomimetic Membrane Systems: Mechanistic Interactions and Hybrid Nano-Lipid Platforms [PDF]
NanomaterialsCarbon dots (CDs) have emerged as a distinct class of fluorescent nanomaterials distinguished by their tunable physicochemical properties, ultrasmall size, exceptional photoluminescence, versatile surface chemistry, high biocompatibility, and chemical ...
Nisreen Nusair, Mithun Bhowmick
doaj +2 more sources
PharmaceuticsDrug delivery selectivity is a challenge for cancer treatment. A hybrid pegylated pH-sensitive liposome–extracellular vesicle isolated from human breast cancer cell MDA-MB-231 was developed to investigate its in vitro activity against breast cancer cells
Luiza Marques Paschoal Barbosa +7 more
doaj +3 more sources
Astrocytes in Paper Chips and Their Interaction with Hybrid Vesicles [PDF]
Advanced Biology, 2022 AbstractThe role of astrocytes in brain function has received increased attention lately due to their critical role in brain development and function under physiological and pathophysiological conditions. However, the biological evaluation of soft material nanoparticles in astrocytes remains unexplored.
Abild Meyer, Cathrine +6 more
openaire +3 more sources