Results 151 to 160 of about 8,191,811 (190)
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Flow Cytometry in Hybridoma Technology
1987The continuous growth in culture of mouse myeloma cells fused to immunized spleen cells was first described by Kohler and Milstein in 1975 (1). The fused hybridoma cells secrete monoclonal antibodies of predefined specificity that arc widely used in biological research and in newly developed clinical applications such as diagnosis and treatment of ...
Michael Andreeff, Edith Espiritu
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Present status and future prospects for the hybridoma technology
In Vitro, 1981A somatic cell genetic technique has recently been developed that makes it possible to obtain very large amounts of homogeneous antibodies and to replenish the supply of the exact same antibodies whenever they are needed. This hybridoma technology has already contributed to major scientific advances and will surely improve the diagnosis and treatment ...
M D, Scharff, S, Roberts
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Biochemistry of hybridoma technology.
Developments in biological standardization, 1987The study of the metabolic requirements of cells in vitro requires both a qualitative definition of such nutrients and a quantitative analysis to optimize cell growth. The development of a rapid weaning procedure which allows cells to be cultured in low serum concentrations, facilitates the easy assessment of factors which regulate cell growth and ...
R, Wilson, R E, Spier
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Between fact and technique: The beginnings of hybridoma technology
Journal of the History of Biology, 1992At several places in this paper we have made use of a well-known rhetorical device: an argument was made; a character —dubbed “fictional reader” — was then evoked who voiced some objections against that particular argument; and finally, we answered those objections, thus bringing to a close, at least temporarily, our argument.
A, Cambrosio, P, Keating
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What's new: Hybridoma technology in immunocytochemistry
BioEssays, 1984AbstractWhat's New will present discussions of new methodologies or improvements of previously developed techniques. In this article, A. C. Cuello and C. Milstein discuss the present status of monoclonal antibody technology..
A. Claudio Cuello, Cesar Milstein
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Idiotype Vaccine Production Using Hybridoma Technology
2014Non-Hodgkin's lymphoma (NHL) is the most common hematological malignancy both in Europe and in the United States. Follicular lymphoma (FL), a tumor comprised of mature B cells, represents one fourth of all NHL and, despite good response rates to standard treatments, tends to frequently relapse to such an extent that it is still considered incurable ...
Susana, Inoges +4 more
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[Current developments in hybridoma technology].
Tijdschrift voor diergeneeskunde, 1986A review of recent developments in hybridoma technology is presented. The advantages and disadvantages of different methods of immunization, immortalization, selection and cultivation of hybridomas are evaluated. Recent and promising developments in the field of the application of monoclonal antibodies are discussed.
A D, Osterhaus, A G, UytdeHaag
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Application of hybridoma technology to the diagnosis of parasitic disease
Veterinary Parasitology, 1984Recent applications of hybridoma-derived monoclonal antibodies to the diagnosis of parasitic disease are reviewed. Diagnostic tests, utilizing monoclonal antibodies, have included radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) techniques to detect parasite antigen in host tissues and body fluids and circulating host antiparasite ...
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Hybridoma technology: a view from the patent arena
Immunology Today, 2000The patenting of biological molecules, such as hybridomas and monoclonal antibodies, has become an important issue in biology. While challenging cherished beliefs and practices of many biologists, it has been a central issue for hybridoma and monoclonal antibody research.
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