Analysis of peptide binding patterns in different major histocompatibility complex/T cell receptor complexes using pigeon cytochrome c-specific T cell hybridomas. Evidence that a single peptide binds major histocompatibility complex in different conformations. [PDF]
Hansha Bhayani, Yvonne Paterson
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Main Points Pre‐exposure prophylaxis (PrEP) inhibits oligodendrocyte differentiation PrEP inhibits oligodendrocyte differentiation through lysosome deacidification Acidic nanoparticles prevent PrEP‐induced inhibition of oligodendrocyte differentiation ABSTRACT A disproportionate percentage of adolescents are diagnosed with human immunodeficiency virus (
Caela C. Long+6 more
wiley +1 more source
Predominant utilization of V beta 8+ T cell receptor genes in the H-2Ld- restricted cytotoxic T cell response against the immediate-early protein pp89 of the murine cytomegalovirus [PDF]
Cytotoxic T cell responses to the murine Cytomegalovirus (MCMV) were elicited in BALB/c mice (H-2d) by infectious virus. Eight days after infection, MCMV-primed local lymph node T cells were either depleted for T cells expressing a V beta 8+ TCR or ...
Eichmann, K.+3 more
core
Cell receptors for the mammalian reovirus: reovirus-specific T-cell hybridomas can become persistently infected and undergo autoimmune stimulation [PDF]
Noboru Matsuzaki+3 more
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Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun+10 more
wiley +1 more source
A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice. [PDF]
We have previously reported that T cells bearing T cell receptors (TCRs) of gamma/delta type appear at a relatively early stage of primary infection with Listeria monocytogenes in mice.
Bluestone, JA+7 more
core
Platelet binding properties of monoclonal lupus autoantibodies produced by human hybridomas [PDF]
T Asano, BC Furie, B Furie
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Immunochemical evidence that human apoB differs when expressed in rodent versus human cells
LDL from human apolipoprotein B-100 (apoB-100) transgenic (HuBTg+/+) mice contains more triglyceride than LDL from normolipidemic subjects. To obtain novel monoclonal antibody (MAb) probes of apoB conformation, we generated hybridomas from HuBTg+/+ that ...
Xingyu Wang+9 more
doaj
The circular dichroism of phosphocholine-specific mouse hybridoma and myeloma proteins: Unusual properties of the hybridoma protein 101.6g6 [PDF]
N. Martin Young+2 more
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Probing How Anti‐huntingtin Antibodies Bind the Fibrillar Fuzzy Coat Using Solid‐State NMR
Antibodies are widely used to recognize, detect, and target aggregated and misfolded amyloid‐forming proteins, including those associated with HD. Studying such interactions on a structural level is a challenge. Parlato and colleagues report on their use of solid‐state NMR and electron microscopy to probe how such antibodies bind to the fuzzy coat of ...
Raffaella Parlato+3 more
wiley +1 more source