Results 131 to 140 of about 23,113 (239)

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source

Searching for Novel COVID19 Treatments: Towards Covalent TMPRSS2 Inhibitors

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
We designed, synthesised, and evaluated new guanidine derivatives as potential covalent inhibitors of TMPRSS2, a key protease for SARS‐CoV‐2 entry. Computational studies showed that some compounds have improved binding over nafamostat. However, experimentally none effectively blocked viral entry in cell assays, indicating further optimisation is needed.
Marco Minneci, Barbara Farkaš, Adeyemi Rahman, Inga Nehlmeier, Amy Eichmann, Stefan Pöhlmann, Isabel Rozas   +6 more
wiley   +1 more source

A monoclonal antibody collection for C. difficile typing ?

Gut Pathogens
Clostridioides difficile is the leading cause of antibiotic-associated diarrhea and pseudomembranous colitis in adults. Various C. difficile strains circulate currently, associated with different outcomes and antibiotic resistance profiles. However, most
Lise Hunault, Patrick England, Frédéric Barbut, Bruno Iannascoli, Ophélie Godon, François Déjardin, Christophe Thomas, Bruno Dupuy, Chunguang Guo, Lynn Macdonald, Guy Gorochov, Delphine Sterlin, Pierre Bruhns   +12 more
doaj   +1 more source

Activation properties of T cell receptor-gamma delta hybridomas expressing diversity in both gamma- and delta-chains.

, 1988
To elucidate the structure, diversity, and activation properties of the murine T3-associated gamma delta-receptor, examination was made of the gamma delta and T3 components, T cell receptor (TCR) gene transcription, activation properties, and lymphokine ...
Pardoll, D, Leo, Oberdan, Coligan, J, Fowlkes, B J, Kruisbeek, A M, Germain, R N, Saito, T, Schwartz, R H, Marusić-Galesić, S   +8 more
core  

Immunological Detection of Newcastle Disease Viral Antigen in the Naturally Infected Chickens by Monoclonal Antibodies against Fusion-2 Protein

Jurnal Veteriner, 2014
Monoclonal antibodies (mAbs) against Fusion (F)2 protein of Newcastle disease virus (NDV) wereproduced for the detection of the viral antigen in infected chickens.
Nyoman Mantik Astawa, Anak Agung Ayu Mirah Adi   +1 more
doaj  

Lysosomal processing of sulfatide analogs alters target NKT cell specificity and immune responses in cancer

The Journal of Clinical Investigation
In a structure-function study of sulfatides that typically stimulate type II NKT cells, we made an unexpected discovery. We compared analogs with sphingosine or phytosphingosine chains and 24-carbon acyl chains with 0-1-2 double bonds (C or pC24:0, 24:1,
Kumiko Nishio, Lise Pasquet, Kaddy Camara, Julia DiSapio, Kevin S. Hsu, Shingo Kato, Anja Bloom, Stewart K. Richardson, Joshua A. Welsh, Tianbo Jiang, Jennifer C. Jones, Susanna Cardell, Hiroshi Watarai, Masaki Terabe, Purevdorj B. Olkhanud, Amy R. Howell, Jay A. Berzofsky   +16 more
doaj   +1 more source

Cross-Reactive Neutralizing Antibodies Between ZIKV and DENV May Exhibit Serotype Specificity. [PDF]

Biotechnol J
Silveira LAD, Saavedra DP, Junqueira IC, Dietz JDC, Oliveira CR, Lopes-Luz L, Chaves LCS, Ribeiro BM.   +7 more
europepmc   +1 more source

Functional Parameters of Hybridoma Cells: Methods of Evaluation and Biotechnological Relevance. [PDF]

Antibodies (Basel)
Bezukladnikova T, Zamorina S, Lazarev S, Rayev M.   +3 more
europepmc   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR-Mediated Control of Immunoglobulin Homeostasis in Hybridomas. [PDF]

Adv Sci (Weinh)
Zou R, Lu X, Liu Y, Yang P, Sun S, Liu Y, Mo Y, Zhu G, Lee JS, Guo Y.   +9 more
europepmc   +1 more source

Establishment of Autoreactive CD4⁺CD8⁺ T Cell Hybridomas from Sjögren's Disease Model, SATB1 Conditional Knockout Mice. [PDF]

Int J Mol Sci
Mashimo S, Arita M, Kuwabara T, Naito T, Takizawa S, Inoue A, Ishiko A, Kondo M, Tanaka Y.   +8 more
europepmc   +1 more source