Results 141 to 150 of about 3,737 (192)
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2005
Hybridomas can be grown in a number of ways to produce stocks of monoclonal antibodies. Smaller volumes may be produced in static flask culture, but if larger amounts are required, a bioreactor may be used.
Gary, Entrican, Gareth, Young
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Hybridomas can be grown in a number of ways to produce stocks of monoclonal antibodies. Smaller volumes may be produced in static flask culture, but if larger amounts are required, a bioreactor may be used.
Gary, Entrican, Gareth, Young
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2015
The generation of hybridoma cell lines by the fusion of splenocytes from immunized mice with immortal myeloma cells is a well-established method for the production of monoclonal antibodies. Although other methods have emerged as an effective alternative for the generation of monoclonal antibodies, the use of hybridoma technology remains a viable ...
Robert M, Hnasko, Larry H, Stanker
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The generation of hybridoma cell lines by the fusion of splenocytes from immunized mice with immortal myeloma cells is a well-established method for the production of monoclonal antibodies. Although other methods have emerged as an effective alternative for the generation of monoclonal antibodies, the use of hybridoma technology remains a viable ...
Robert M, Hnasko, Larry H, Stanker
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2005
Hybridomas are derived from the fusion of spleen and myeloma cells and produce monoclonal antibodies. Each hybridoma cell line produces an antibody with a unique specificity allowing the production of highly defined reagents that can be used in many branches of immunochemistry.
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Hybridomas are derived from the fusion of spleen and myeloma cells and produce monoclonal antibodies. Each hybridoma cell line produces an antibody with a unique specificity allowing the production of highly defined reagents that can be used in many branches of immunochemistry.
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Monoclonal Antibodies of Hybridomas
Clinical Infectious Diseases, 1983Among the most prominent biological advances of this century, the hybridoma technology stands out as providing the best tool for the analysis of complex antigens of pathogens and tumor cells. This technology will play a major role in the immunodiagnosis and treatment of infectious and malignant diseases.
J G, Sinkovics, G R, Dreesman
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Generation and maintenance of hybridomas
Immunology Today, 1987The realization of the therapeutic potential of monoclonal antibodies will depend on the efficient generation and maintenance of hybridomas. At a recent workshop on the Stability and Viability of Antibody-Producing Cell Lines it was clear that there are still large gaps in the knowledge needed to achieve that aim.
J F, Albright, M D, Scharff
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Hybridomas As a Source of Antibodies
Hospital Practice, 1981Hybridomas, the progeny of fusion between antibody-secreting spleen cells and myeloma cells, produce large quantities of a single species of antibody. They are an ideal source of serologic reagents since they can be grown in tissue culture, frozen, stored, and recovered when needed.
M D, Scharff, S, Roberts, P, Thammana
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European Journal of Immunology, 1984
AbstractA hybridoma is described that exhibits all the characteristic features of Mott cells. It has spherules (Russell bodies) in the cytoplasm made up of dilated rough endoplasmatic reticulum and containing condensed immunoglobulin (λ1 light chains). Some of the cells appear to be very fragile, and free spherules are often found on cell smears. Cells
Weiss, S. +3 more
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AbstractA hybridoma is described that exhibits all the characteristic features of Mott cells. It has spherules (Russell bodies) in the cytoplasm made up of dilated rough endoplasmatic reticulum and containing condensed immunoglobulin (λ1 light chains). Some of the cells appear to be very fragile, and free spherules are often found on cell smears. Cells
Weiss, S. +3 more
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In Vitro, 1981
partnership. Just as this new facility symbolizes the vigor of the ATCC, so this conference symbolizes the communal interest that must be accorded the preservation and distribution of microorganisms and other cell lines. The ATCC and other repositories are not simply means to facilitate the sharing of cells of contemporary interest.
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partnership. Just as this new facility symbolizes the vigor of the ATCC, so this conference symbolizes the communal interest that must be accorded the preservation and distribution of microorganisms and other cell lines. The ATCC and other repositories are not simply means to facilitate the sharing of cells of contemporary interest.
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In Vitro, 1981
The National Institute of Allergy and Infectious Diseases is developing, with the American Type Culture Collection, a central facility for the acquisition, maintenance, and distribution of hybridoma cell lines. This effort finds its principal justification in the great activity in this field and in the large variety of hybridoma lines that are produced
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The National Institute of Allergy and Infectious Diseases is developing, with the American Type Culture Collection, a central facility for the acquisition, maintenance, and distribution of hybridoma cell lines. This effort finds its principal justification in the great activity in this field and in the large variety of hybridoma lines that are produced
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Creating hybridomas by electrofusion
Nature, 1988Electromanipulation has long been used to form pores in cell membranes to transfect them with foreign DNA. Now, the technique has been extended to the preparation of hybridomas.
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