Results 111 to 120 of about 23,113 (239)

Randomised controlled phase I trial of a SARS‐CoV‐2 monoclonal antibody

Clinical &Translational Immunology, Volume 15, Issue 11, 2026.
Abstract Objectives SARS‐CoV‐2 infection remains a threat to vulnerable groups. Neutralising monoclonal antibodies (mAbs) have shown efficacy in the treatment and prevention of COVID‐19, but most mAbs have lost activity against recent Omicron strains.
Wen Shi Lee, Kevin J Selva, Timothy E Schlub, Jennifer Audsley, Janavi S Rambhatla, Robyn Esterbauer, Jennifer A Juno, Andrew Kelly, Ellie Reilly, Thakshila Amarasena, Sarah Lee, Hyon‐Xhi Tan, Chee Wah Tan, Lin‐Fa Wang, Christina C Chang, Michael Gerometta, Judith A Scoble, Patrick F James, Arnold Reynaldi, Miles P Davenport, Kym Hoger, Karen Hughes, Martina L Jones, Ben Hughes, Adam K Wheatley, Stephen J Kent   +25 more
wiley   +1 more source

A Study of Cell-Surface Characteristics of Macrophage Hybridomas and How tthey are Affected by Activation of the Macrophage Hybridomas with Gamma-Interferon

, 1986
vii, 62 p.A series of macrophage hybridomas were geerated by fusion of splenic adherent cells with macrophage P388Dl tumor cells. The production of such a series of macrophage clones is of great assistance in analyzing macrophage biology and dissecting ...
Ahmed, Eqbal
core  

Rescue Strategy for Nonviable Hybridomas: Amplifying Heavy- and Light-Chain Sequences from Genomic DNA by Polymerase Chain Reaction

, 2017
Many hybridoma researchers have lost an important hybridoma because of instability, mechanical breakdown of a freezer, or contamination. In many cases, however, it is possible to retrieve the heavy- and light-chain sequences from those hybridomas ...
James R. Dasch, Amy L. Dasch
core   +1 more source

M11‐CAR T cells inhibit murine cytomegalovirus in vitro upon recognition of virion‐ and cell‐associated glycoprotein B

Clinical &Translational Immunology, Volume 15, Issue 11, 2026.
Abstract Objectives Viral infections are predominantly managed with conventional antiviral drugs, which, despite their efficacy, can cause toxicity and promote resistance. Cell‐based immunotherapies offer an alternative, but cytomegaloviruses (CMV) profoundly interfere with MHC class I antigen presentation, thereby impairing conventional virus‐specific
Sabrina Kübel, Christopher Garçon, Hanna Menschikowski, Arne Cordsmeier, Jens‐Christian Albrecht, Friederike Oltmanns, Larissa Bauer, Manuel Hermann, Kristina Holdt, Heinrich Sticht, Marco Thomas, Thomas H Winkler, Brigitte Scholz, Doris Jungnickl, Armin Ensser   +14 more
wiley   +1 more source

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

Glia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis, Breana C. Dogan, Amy L. Stanek, Elliot B. Evans, Madelyn G. Coble, Hayli E. Spence‐Osorio, Karen L. G. Farizatto, Angie L. Mordant, C. Allie Mills, Laura E. Herring, Katherine T. Baldwin   +10 more
wiley   +1 more source

SUPPLEMENTARY_INFORMATION-Lijie-Development_of_bacterial_macroarrays_for_the_rapid_screening_of_targeted_antibody-secreted_hybridomas – Supplemental material for Development of a Bacterial Macroarray for the Rapid Screening of Targeted Antibody-Secreted Hybridomas

, 2018
Supplemental material, SUPPLEMENTARY_INFORMATION-Lijie-Development_of_bacterial_macroarrays_for_the_rapid_screening_of_targeted_antibody-secreted_hybridomas for Development of a Bacterial Macroarray for the Rapid Screening of Targeted Antibody-Secreted ...
XuZhao Zhai (5847020), Dongpo Xu (1700188), Chengchao Ding (5847023), Qing Liu (20889), Xiang Wang (127867), Yali Liu (12074), Qingli Dong (5847026), Jing Pan (95938), Jie Li (15030), Qi Zhang (28502), Jingxuan Qiu (728331)   +10 more
core   +1 more source

Development and Evaluation of Monoclonal Antibodies against CBPP Antigen with the End Goal of Developing an ELISA Kit

Veterinary Medicine International
Contagious bovine pleuropneumonia (CBPP) is an infectious and contagious bacterial respiratory disease that affects cattle with significant economic losses to the African animal industry.
Lorato Ramathudi-Dunbar, Emmanuel Awosanya, Sanne Bodjo Charles, Ethel Chitsungo, Cisse Rahamatou Moustapha Boukary, Nick Nwankpa, Hassen Gelaw, Yebechaye Tessema, Gelagay Melesse A., Richard Rayson Sanga, Adorbley Bright, Jean de Dieu Baziki   +11 more
doaj   +1 more source

Brain‐Derived Neurotrophic Factor (BDNF), Estrogen Receptors, and Mossy Cells

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT Dentate gyrus (DG) function depends on the neurotrophin brain‐derived neurotrophic factor (BDNF) which shows robust synthesis in the principal cells, the granule cells (GCs). However, BDNF protein is present in the inner molecular layer (IML), where most afferents to GCs are from hilar mossy cells (MCs). Therefore, we asked whether MCs express
Chiara Criscuolo, Monarchsinh Rathod, Fang Jie, Helen E. Scharfman   +3 more
wiley   +1 more source

More efficient generation of neutralizing hybridomas against IL-21 from the alternating-antigen approach.

, 2019
(A, C, and E) hybridomas isolated from the alternating antigen approach. (B, D and F) hybridomas isolated from the single antigen approach. (A, B) Binding ELISA results of human and cyno IL-21 cross-reactive hybridoma supernatants.
Rachel Ettinger (6264008), Herren Wu (166537), Melissa Damschroder (166551), Reena Varkey (6263996), Xiaodong Xiao (360835), Qun Du (6263999), Rob Woods (1536871), William F. Dall’Acqua (654947), Kim Rosenthal (694648), Ronald Herbst (611168), Kerry A. Casey (6264005), Susan Wilson (134263), Jodi L. Karnell (6264002)   +12 more
core   +1 more source

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas

, 1992
Udgivelsesdato: 1992-Jan-15We have generated cloned Th1 cells, Th2 cells, and T cell hybridomas specific for the single immunogenic peptide from the beta-chain of murine hemoglobin (Hb(64-76)).
Hsu, B L, Allen, P M, Williams, S G, Buus, S, Evavold, B D   +4 more
core   +1 more source