Results 101 to 110 of about 3,737 (192)

Diving into the unknown: Evidence of enhanced skeletal muscle lactate efflux potential and blood–muscle exchange in competitive breath‐hold divers

The Journal of Physiology, EarlyView.
Abstract figure legend Competitive breath‐hold divers exhibit skeletal muscle characteristics indicative of enhanced blood‐muscle exchange capacity and increased lactate efflux potential. Top left: Participant characteristics, matched for age, height, body mass, and maximal oxygen uptake (V̇O2max${\dot{\mathrm{V}}}\rm{O}_{\rm{2max}}$).
Antonis Elia, Matthew Lees, John O'Hara, Nathan Hodson, Jordan Acheson, Oliver Wilson, Paul Parker, Matthew Barlow   +7 more
wiley   +1 more source

Identification and validation of genes encoding humoral specificity for the chemical allergen toluene diisocyanate.

PLoS ONE
A panel of hybridomas specific for different isomers of toluene diisocyanate (TDI), a cross‑linking chemical used in polyurethane production, has been previously described.
Adam V Wisnewski, Jian Liu
doaj   +1 more source

Production of Monoclonal Antibodies Against the Challenge Strain of Infectious Laryngotracheitis Virus of Chickens and Their Use in an Indirect Immunofluorescent Diagnostic Test [PDF]

Pakistan Veterinary Journal, 2010
The objective of the present research was to produce monoclonal antibodies (MCAs) against the USDA challenge strain of infectious laryngotracheitis virus and to perform an initial investigation of their use in an indirect immunofluorescence diagnostic ...
Ferhat Abbas*, James Andreasen1, Rockey Becker1, Masroor Ahmed, M Arif Awan, Abdul Wadood and Anita Sonn1
doaj  

Introduction of Genes for Drug Tolerance into Human-Human Hybridomas by Electroporation

, 1990
We examined the effect of gene transfer into human-human hybridomas by electroporation on their production of immunoglobulin. Drug-resistant hyblidomas were easily obtained after transfection of hybridomas with the pSV2-neo or Eco gpt-E1A plasmid DNA by ...
立花, 宏文, Shirahata, Sanetaka, 白畑, 実隆, Tachibana, Hirofumi, Yamada, Koji, 村上, 浩紀, Murakami, Hiroki, 山田, 耕路   +7 more
core  

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

Glia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis, Breana C. Dogan, Amy L. Stanek, Elliot B. Evans, Madelyn G. Coble, Hayli E. Spence‐Osorio, Karen L. G. Farizatto, Angie L. Mordant, C. Allie Mills, Laura E. Herring, Katherine T. Baldwin   +10 more
wiley   +1 more source

Novel BCR-Targeting Fusion Proteins for Antigen-Specific Depletion of Alloreactive B Cells in Antibody-Mediated Rejection

Cells
Donor-specific anti-HLA antibodies (DSAs) bind to donor vascular endothelial cells and mediate allograft rejection (AMR), but a clinical challenge for which targeted therapeutic options remain limited.
Jing Zhang, Leiyan Wei, Lei Song, Xiaofang Lu, Liang Tan, Xin Li, Li Fu, Qizhi Luo, Xubiao Xie, Yizhou Zou   +9 more
doaj   +1 more source

Enhancement of limiting dilution in cloning mouse myeloma-spleen hybridomas by human low density lipoproteins [PDF]

, 2009
[[abstract]]The limiting dilution technique is a critical step in the cloning of hybridomas for the preparation of monoclonal antibodies. We have found that culture medium supplemented with human plasma low density lipoproteins (LDL) markedly enhanced ...
Mao SJT;France DS.
core  

Genetic and Pharmacologic Inhibition of Myostatin Restores Muscle Mass in a Dynamin 2‐Related Centronuclear Myopathy Mouse Model

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Autosomal dominant centronuclear myopathy (ADCNM), most commonly caused by mutations in the dynamin 2 (DNM2) gene, is a rare congenital myopathy characterized by progressive muscle weakness and atrophy. Myostatin, a key negative regulator of skeletal muscle mass, has shown therapeutic potential in several models of neuromuscular ...
Durieux Anne‐Cécile, Arnould David, Velarde Mathias, Allibert Valentine, Paret Chloé, Debelley Quentin, Kizilkilic Esra, Chambon Sidney, Girard Emmanuelle, Collin Louise, Gensel Alexandre, Castells Josiane, Pasternack Aja, Bowen Maximilien, Morel Baptiste, Hourdé Christophe, Laurent Schaeffer, Ritvos Olli, Bitoun Marc, Mounier Rémi, Freyssenet Damien   +20 more
wiley   +1 more source

Anti‐idiotypic antibodies as molecular mimics of conserved influenza hemagglutinin epitopes

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Broadly neutralizing antibodies (bNAbs) provide insights for developing universal influenza vaccines through their ability to neutralize diverse viral strains. However, designing antigens that reliably elicit bNAb responses remains challenging due to the difficulty in targeting conserved epitopes with a single antigen.
Hiroshi Itou, Kaori Sano, Akira Ainai, Kazushige Otsuki, Toshikazu Inoue, Takuya Hemmi, Hideki Hasegawa, Tadaki Suzuki   +7 more
wiley   +1 more source

A Study of Cell-Surface Characteristics of Macrophage Hybridomas and How tthey are Affected by Activation of the Macrophage Hybridomas with Gamma-Interferon

, 1986
vii, 62 p.A series of macrophage hybridomas were geerated by fusion of splenic adherent cells with macrophage P388Dl tumor cells. The production of such a series of macrophage clones is of great assistance in analyzing macrophage biology and dissecting ...
Ahmed, Eqbal
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