Results 81 to 90 of about 19,999 (251)

Development and characterization of murine monoclonal antibody specific for the P1.4 PorA proteins from strain B:4:P1.(7b).4. of Neisseria meningitidis

open access: yesVacciMonitor, 2011
Neisseria meningitidis isolates are conventionally classified by serosubtyping that characterizes the reactivities of the PorA outer membrane protein variable-region epitopes with monoclonal antibodies.
María Elena Pérez   +8 more
doaj  

In vitro invasiveness of CTL clones and in vivo dissemination of CTL hybridomas

open access: yes, 1993
Activated spleen T cells are invasive in hepatocyte and fibroblast cultures, and this property is dominantly expressed in T cell hybridomas. The invasive potential of the hybrids correlates with their capacity to disseminate in vivo.
Geertie La Rivière   +4 more
core   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

open access: yesThe FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia   +7 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon   +12 more
wiley   +1 more source

Generation and Characterization of Hybridomas from HUG Transgenic JH Knockout Mice and JH Knockout Mice.

open access: yes, 2003
Dr. Pollock?s lab studies transgenic mice that express a mouse/human chimeric antibodies (immunoglobulin) heavy chain gene called HUG. We want to determine the effect of the HUG heavy chain on expression of the mouse?s endogenous immunoglobulin (Ig ...
Yatsubo, Sayuri
core  

Secondary cartilage in the murine medial pterygoid plate has a critical role in the pathfinding of the tensor veli palatini

open access: yesJournal of Anatomy, EarlyView.
The development of the medial pterygoid plate (MPP) is followed in mouse embryos, highlighting its neural crest origin and complex development via both endochondral and membranous ossification. Using transgenic mice, the secondary cartilage of the MPP is shown to direct the path of the tensor veli palatini.
Luke A. Barlow   +2 more
wiley   +1 more source

Influence and convergence to higher standards: The dual examination of pharmaceutical patents in Brazil

open access: yesThe Journal of World Intellectual Property, EarlyView.
Abstract Between 2001 and 2021, pharmaceutical patent applications filed in Brazil were examined by the patent office (INPI) and the national health regulator (Anvisa). This paper investigates how health regulators can contribute to patent examination by shifting the set of criteria cited as grounds for 2589 negative decisions from both entities ...
Eduardo Mercadante
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

More efficient generation of neutralizing hybridomas against IL-21 from the alternating-antigen approach.

open access: yes, 2019
(A, C, and E) hybridomas isolated from the alternating antigen approach. (B, D and F) hybridomas isolated from the single antigen approach. (A, B) Binding ELISA results of human and cyno IL-21 cross-reactive hybridoma supernatants.
Rachel Ettinger (6264008)   +12 more
core   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar   +15 more
wiley   +1 more source

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