Results 61 to 70 of about 23,113 (239)
Development of a new monoclonal antibody specific to mouse Vγ6 chain
Life Science Alliance, 2019 Using a novel mAb specific to Vγ6 TCR, we find Vγ6 + γδT cells are located in association with medullary thymic epithelial cells and play crucial roles in protection against Klebsiella pneumoniae infection but are pathogenic in psoriasis-like dermatitis ...
Shinya Hatano +7 more
doaj +1 more source
Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle
Developmental Dynamics, EarlyView.Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell +3 more
wiley +1 more source
Three‐dimensional observation of the muscle–tendon integration process in mouse embryos
Developmental Dynamics, EarlyView.Abstract Background Muscle–tendon integration is a crucial step in the morphogenesis of the vertebrate locomotion system. As the limb muscle and tendon progenitor cells derive from distinct embryonic origin, their integration requires precise mutual positioning.
Ramu Sagasaki +10 more
wiley +1 more source
, 1981 Thirteen hybridomas producing 2,4,6-trinitrophenyl-(TNP)-specific mouse IgE of Iga or Igb haplotype are described. They are freely available.
Burrows, P., Rudolph, A., Wabl, M.
core +1 more source
Immunochemical evidence that human apoB differs when expressed in rodent versus human cells
Journal of Lipid Research, 2003 LDL from human apolipoprotein B-100 (apoB-100) transgenic (HuBTg+/+) mice contains more triglyceride than LDL from normolipidemic subjects. To obtain novel monoclonal antibody (MAb) probes of apoB conformation, we generated hybridomas from HuBTg+/+ that ...
Xingyu Wang +9 more
doaj +1 more source
Veterinary Record, EarlyView.Abstract Background Pet ferrets are typically vaccinated against distemper using a canine multivalent vaccine despite the lack of relevant safety or efficacy data. Here, we investigate the safety of a novel live canine parvovirus type 2c (CPV‐2c) vaccine strain and the efficacy of the live Onderstepoort canine distemper virus (CDV) vaccine strain used ...
Jacqueline Pearce +4 more
wiley +1 more source
In vitro invasiveness of CTL clones and in vivo dissemination of CTL hybridomas
, 1993 Activated spleen T cells are invasive in hepatocyte and fibroblast cultures, and this property is dominantly expressed in T cell hybridomas. The invasive potential of the hybrids correlates with their capacity to disseminate in vivo.
Geertie La Rivière +4 more
core +1 more source
Human IgE Antibodies Recognize the Vicilin and Alpha‐Hairpinin Domains of Peanut Allergen Ara h 1
Allergy, EarlyView.The ɑ‐hairpinin of Ara h 1 contains a dominant epitope that is both frequently recognized and blocks a majority of the IgE against this domain. Including this region in tests may improve diagnosis of peanut allergy. The trimeric structure of the vicilin region explains the ability of Ara h 1 to induce anaphylaxis with a single antibody.
Taylor M. Cosey +14 more
wiley +1 more source
, 2001 The possibility that immortalisation of in vitro immunised splenocytes may result in hybridomas secreting polyreactive antibodies was investigated.
Michael J McMahon +3 more
core +1 more source
Antibodies, 2020 Poliovirus (PV)-specific intestinal IgAs are important for cessation of PV shedding in the gastrointestinal tract following an acute infection with wild type or vaccine-derived PV strains.
Rama Devudu Puligedda +8 more
doaj +1 more source