The role of Ia molecules in the activation of T lymphocytes. III. Antigen-specific, Ia-restricted, interleukin 2-producing T cell hybridomas with detectable affinity for the restricting I-A molecule. [PDF]
Kenneth L. Rock, Baruj Benacerraf
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Single‐cell RNA sequencing of enzymatically dissociated human lymph node stromal cells (LNSCs) reveals transcriptional and spatial heterogeneity. Following cell sorting and phenotyping, stromal subsets were validated across multiple datasets, mapped within lymph node architecture, and analyzed for subset‐specific immune interactions, enabling a ...
Cristoforo Grasso+9 more
wiley +1 more source
The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. [PDF]
J L Greenstein+3 more
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A 10‐Year Longitudinal Study of Muscle Morphology and Performance in Masters Sprinters
ABSTRACT Background Both longitudinal and cross‐sectional studies have demonstrated that muscle mass, strength and power are lost with ageing. Although longitudinal studies have shown changes in muscle morphology and function in sedentary, healthy active and endurance‐trained older people, less is known about such age‐related changes in sprint athletes.
P. W. Hendrickse+3 more
wiley +1 more source
Interlab Cell Line Collection: Bioresource of Established Human and Animal Cell Lines
The Interlab Cell Line Collection (ICLC) was established in 1994 as a core facility of the National Institute of Cancer Research. It supplies: human and animal cell lines; Short Tandem Repeat (STR) profiling of human cell lines; quality control service ...
Barbara Parodi+4 more
doaj
Fiber Type‐Specific Proteomic Alterations in R349P Desminopathy Mice
ABSTRACT Introduction/Aims Desminopathies are a group of rare human myopathies and cardiomyopathies caused by pathogenic variants of the desmin gene. Here, we analyzed the effects of the R349P mutant desmin on the proteomic profiles of individual fiber types of murine skeletal muscle.
Britta Eggers+7 more
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Generation of the first monoclonal antibody using mouse hybridomas
Brunangelo Falini
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Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor Vβ-specific antibodies [PDF]
Experimental allergic encephalomyelitis (EAE) is a model system for T cell-mediated autoimmune disease. Symptoms of EAE are similar to those of multiple sclerosis (MS) in humans.
Hood, Leroy+3 more
core
Myostatin Knockout Mice Have Larger Muscle Fibers With Normal Function and Morphology
ABSTRACT Introduction We assessed whether muscle fibers in myostatin knockout (MSTN−/−) mice are just larger or also exhibit morphological, metabolic, and functional differences from MSTN+/+ mice. Methods We compared single fiber contractile properties and histological fiber properties in muscles from MSTN−/− and MSTN+/+ mice.
Hans Degens, Ketan Patel, A. Matsakas
wiley +1 more source
A monoclonal antibody collection for C. difficile typing ?
Clostridioides difficile is the leading cause of antibiotic-associated diarrhea and pseudomembranous colitis in adults. Various C. difficile strains circulate currently, associated with different outcomes and antibiotic resistance profiles. However, most
Lise Hunault+12 more
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