Results 161 to 170 of about 55,509 (296)

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 2, Page 127-143, March 2026.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

CHO Cell Line Selection through Multi‐Criteria Analysis Reveals Critical Impact of Gas Overlay

Biotechnology Journal, Volume 21, Issue 3, March 2026.
Graphical Abstract and Lay Summary Multivariate data analysis (MVDA) integrated productivity, growth, stability, and metabolism to rank monoclonal antibody producing CHO clones. From 24 candidates cultivated in well plates, eight were selected for bioreactor experiments. Bioreactor cultures without air overlay had increased pCO2 and unexpectedly better
Jimmy Gaudreault, Petko Komsalov, Jason Kuipers, Lucas Lemire, Brian Cass, Linda Lamoureux, Julien Leroy, Christopher Corbeil, Traian Sulea, Robert Voyer, Simon Joubert, Yves Durocher, Olivier Henry, Phuong Lan Pham   +13 more
wiley   +1 more source

Establishment of Autoreactive CD4⁺CD8⁺ T Cell Hybridomas from Sjögren's Disease Model, SATB1 Conditional Knockout Mice. [PDF]

Int J Mol Sci
Mashimo S, Arita M, Kuwabara T, Naito T, Takizawa S, Inoue A, Ishiko A, Kondo M, Tanaka Y.   +8 more
europepmc   +1 more source

A glomerular permeability factor produced by human T cell hybridomas.

Kidney International, 1991
A. Koyama, M. Fujisaki, Masaki Kobayashi, M. Igarashi, M. Narita   +4 more
semanticscholar   +1 more source

Bottom‐Up Ice Growth Geometry Attenuates Shear Stress and Improves the Cryopreservation of Hematopoietic Stem/Progenitor Cells Under Low DMSO Concentrations

Biotechnology and Bioengineering, Volume 123, Issue 3, Page 582-597, March 2026.
ABSTRACT Studies on cell cryopreservation have been limited by the complexity of the freezing process and challenges on controlling ice formation, managing cooling rates, and optimizing cryoprotectant concentrations. The objective of this study is to evaluate the impact of bottom‐up and conventional radial freezing on the viability of mammalian cells ...
Rafaela Ouro Neves, Pedro Sena Rego, Marta H. G. Costa, Isabel Bogalho, Andreia Duarte, Claúdia L. da Silva, Frederico Castelo Ferreira, Vitor Geraldes, Miguel A. Rodrigues   +8 more
wiley   +1 more source

Inducible immortalized Dendritic Cells enable antigen-specific antibody production in a murine in vitro Immunization model. [PDF]

PLoS One
Egert J, Maier N, Micheel B, Hanack K.
europepmc   +1 more source

Localization of Puncta Adherentia Junctions at GABAergic Synapses on Parvalbumin‐Positive GABAergic Inhibitory Neurons in the Mouse Hippocampus

Journal of Comparative Neurology, Volume 534, Issue 3, March 2026.
Puncta adherentia junctions (PAJs) were observed not only at glutamatergic excitatory synapses on excitatory neurons (E→E synapses) but also at glutamatergic synapses on GABAergic inhibitory neurons (E→I synapses) and at GABAergic synapses on excitatory (I→E synapses) and inhibitory neurons (I→I synapses) in cultured mouse hippocampal neurons.
Kimitaka Katanazaka, Hajime Shiotani, Muneaki Miyata, Takeshi Kameyama, Shin Kedashiro, Ryouhei Komaki, Shota Nishii, Yutaro Kashiwagi, Yuka Sato, Shigeo Okabe, Norio Chihara, Riki Matsumoto, Kiyohito Mizutani, Yoshimi Takai   +13 more
wiley   +1 more source

Non‐cognate CD8 Binding to MHC I Promotes Positive Selection of an MHC‐E Restricted CD8 T Cell Population

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Mouse Qa1b‐restricted T cells show promiscuous requirements for positive selection. Using in vivo tetramer enrichment, in vitro APC engineering, and in vitro thymocyte stimulation, we demonstrate that a Qa1b‐restricted T cell population can be selected by both Qa1b and H2‐T11, and depends on non‐cognate CD8‐MHC I binding.
Xiaokun Yang, Melissa A. Colden, Rachel Coombs, Kathya Arana, Dan Tran, Michael Manoharan Valerio, Ellen A. Robey, Laurent Coscoy   +7 more
wiley   +1 more source

Optimal murine CD4⁺ T cell priming by mRNA-lipid nanoparticle vaccines requires endogenous antigen processing. [PDF]

Nat Commun
Rood JE, Yoon SK, Heard MK, Carro SD, Hedgepeth EJ, O'Mara ME, Hogan MJ, Le N, Muramatsu H, Lam K, Schreiner P, Kasden C, Stedman HH, Langlois RA, Heyes J, Pardi N, Eisenlohr LC.   +16 more
europepmc   +1 more source

Hybridoma [PDF]

, 2020
openaire   +1 more source