Results 171 to 180 of about 60,260 (340)

Nanomaterial‐Enhanced Biosensing: Mechanisms and Emerging Applications

Advanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
Nanomaterial integration transforms biosensor capabilities through enhanced signal transduction, sensitivity, and selectivity. This review analyzes how nanoscale materials—from nanoparticles to nanosheets—leverage unique physicochemical properties to revolutionize electrochemical, optical, and electrical biosensing.
Younghak Cho, Yunyoung Choi, Yerim Jang, Hyejeong Seong   +3 more
wiley   +1 more source

Organoid Modeling of Mouse Anterior Tongue Epithelium Reveals Regional and Cellular Identities

Advanced Science, Volume 12, Issue 46, December 11, 2025.
The tongue's anterior epithelium is maintained by region‐specific stem/progenitor cells, yet in vitro models are limited. Long‐term expanding organoids are developed from adult mouse anterior tongue that retain region‐specific identity, cellular diversity, and gene regulatory features. These organoids differentiate into keratinocytes, Merkel‐like cells,
Seok‐Young Kim, Laurens H. G. Verweij, Lin Lin, Johan H. van Es, Jay Slack, Chris Winkel, Tito Candelli, Philip Lijnzaad, Thanasis Margaritis, Gerben E. Breimer, Karin Sanders, Marc van de Wetering, Hans Clevers   +12 more
wiley   +1 more source

Analysis of thymocyte MHC specificity with thymocyte hybridomas. [PDF]

, 1984
E T Yeh, Baruj Benacerraf, Kenneth L. Rock   +2 more
openalex   +1 more source

Lysosomal processing of sulfatide analogs alters target NKT cell specificity and immune responses in cancer

The Journal of Clinical Investigation
In a structure-function study of sulfatides that typically stimulate type II NKT cells, we made an unexpected discovery. We compared analogs with sphingosine or phytosphingosine chains and 24-carbon acyl chains with 0-1-2 double bonds (C or pC24:0, 24:1,
Kumiko Nishio, Lise Pasquet, Kaddy Camara, Julia DiSapio, Kevin S. Hsu, Shingo Kato, Anja Bloom, Stewart K. Richardson, Joshua A. Welsh, Tianbo Jiang, Jennifer C. Jones, Susanna Cardell, Hiroshi Watarai, Masaki Terabe, Purevdorj B. Olkhanud, Amy R. Howell, Jay A. Berzofsky   +16 more
doaj   +1 more source

Glia Preserve Their Own Functions While Compensating for Neighboring Glial Cell Dysfunction

Glia, Volume 73, Issue 12, Page 2427-2444, December 2025.
Main Points When cortex glia lose their interactions with neuronal cell bodies, all neighboring glia infiltrate the region to clear extra neuronal corpses. Even while compensating tor nearby glial dysfunction, glia maintain their own phagocytic Tunctions.
Allison N. Beachum, Gabriela Salazar, Amelia Nachbar, Kevin Krause, Hannah Klose, Kate Meyer, Ariana Maserejian, Grace Ross, Hannah Boyd, Thaddeus Weigel, Lydia Ambaye, Hayes Miller, Hannah Grote, Jaeda Coutinho‐Budd   +13 more
wiley   +1 more source

Development of a bispecific monoclonal antibody to pesticide carbofuran and triazophos using hybrid hybridomas.

Journal of Food Science, 2009
R. Jin, Y. R. Guo, C. M. Wang, J. Wu, G. Zhu   +4 more
semanticscholar   +1 more source

Functional differences between CLL‐ and ALL‐derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL‐10 as potential modulatory targets

HemaSphere, Volume 9, Issue 12, December 2025.
Abstract Despite advances in targeted therapies, treatment of chronic lymphocytic leukemia (CLL) remains challenging, highlighting the urgent need for effective new therapeutic strategies. Although chimeric antigen receptor (CAR) T‐cell therapy dramatically improved outcomes in acute lymphoblastic leukemia (ALL), its efficacy in CLL is limited.
Janin Dingfelder, Michael Aigner, Jana Lindacher, Pascal Lukas, Cindy Flamann, Gina Nusser, Katharina Zimmermann, Axel Schambach, Frederik Graw, Simon Völkl, Heiko Bruns, Manuela Krumbholz, Martina Haibach, Jochen Wilke, Andreas Mackensen, Gloria Lutzny‐Geier   +15 more
wiley   +1 more source

Activation of a T cell hybridoma by an alloligand results in differential effects on IL-2 secretion and activation-induced cell death [PDF]

, 2001
Ayub Qadri, E. Sally Ward
openalex   +1 more source

Alternative Splicing of SORBS1 Affects Neuromuscular Junction Integrity in Myotonic Dystrophy Type 1

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Myotonic dystrophy type 1 (DM1) is a multisystemic neuromuscular disorder characterized by CTG repeat expansion in the 3′ untranslated region of the dystrophia myotonica protein kinase coding gene. The presence of expanded CTG repeats in DMPK mRNAs leads to the sequestration of RNA‐binding factors such as the Muscleblind‐like (MBNL)
Caroline Hermitte, Hortense de Calbiac, Gilles Moulay, Antoine Mérien, Jeanne Lainé, Hélène Polvèche, Michel Cailleret, Stéphane Vassilopoulos, Edor Kabashi, Denis Furling, Cécile Martinat, Morgan Gazzola   +11 more
wiley   +1 more source

Cloning and Characterization of a Hybridoma Secreting a 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Specific Monoclonal Antibody and Recombinant F(ab) [PDF]

, 2013
Heather Wanczyk, Tolga Barker, Debra Rood, Daniel Zapata, Amy R. Howell, Stewart K. Richardson, John W. Zinckgraf, Gregory Marusov, Michael A. Lynes, Lawrence K. Silbart   +9 more
openalex   +1 more source