Results 31 to 40 of about 4,496 (180)

3-Methyl-5,5-diphenylimidazolidine-2,4-dione

open access: yesIUCrData, 2017
In the title molecule, C16H14N2O2, the imidazolidine-2,4-dione ring carries two phenyl substituents at the 5-position inclined to the five-membered ring plane by 59.17 (6) and 53.21 (6)°.
Walid Guerrab   +5 more
doaj   +1 more source

Synthesis of hydantoin and thiohydantoin related compounds from benzil and study of their cytotoxicity [PDF]

open access: yesBangladesh Journal of Pharmacology, 2006
Condensation of benzil (1) with urea, monophenyl urea and diphenyl urea in the presence of absolute ethanol using 30% aqueous NaOH gave the products 1a, 1b and 1c respectively and also with thiourea, monomethyl thiourea, dimethyl thiourea and diethyl ...
A. Kashem Liton and M. Rabiul Islam
doaj  

Novel Lipophilic Hydroxamates Based on Spirocarbocyclic Hydantoin Scaffolds with Potent Antiviral and Trypanocidal Activity

open access: yesPharmaceuticals, 2023
Flaviviridae infections, such as those caused by hepatitis C (HCV) and dengue viruses (DENVs), represent global health risks. Infected people are in danger of developing chronic liver failure or hemorrhagic fever, both of which can be fatal if not ...
Vasiliki Pardali   +8 more
doaj   +1 more source

Synthesis and Crystal Structures of 1,1′-Methylene-bis(imidazolidine-2,4-dione) and Alkali Metal Salts

open access: yesCrystals, 2014
Single-crystal structures of 1,1′-methylenebis(imidazolidine-2,4-dione) and its sodium and dipotassium salts were determined. Powder X-ray diffraction was also employed to characterize the bulk materials and those phases which did not yield single ...
Robert Salchner   +6 more
doaj   +1 more source

Investigation of the GnRH antagonist degarelix isomerization in biological matrices

open access: yesPharmacology Research & Perspectives, 2023
One of the main objectives of peptide drug design is the improvement of peptide pharmacokinetics with maintaining biological activity, which can be achieved by the complex modifications of the primary structure of the peptides.
Lucia Ferrazzano   +6 more
doaj   +1 more source

Crystal structures of (S)-(+)-5-(3-bromo/chloro-4-isopropoxyphenyl)-5-methylimidazolidine-2,4-dione

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
In (S)-(+)-5-(3-bromo-4-isopropoxyphenyl)-5-methylimidazolidine-2,4-dione, C13H15BrN2O3, (I), the hydantoin groups are connected via intermolecular N—H...O hydrogen bonds, forming a terraced sheet structure.
Shigeru Ohba   +3 more
doaj   +1 more source

Drug-Induced Changes in the Gingival Tissue

open access: yesJournal of Interdisciplinary Medicine, 2023
Drug-induced gingivitis is caused by the administration of certain drugs such as hydantoin, calcium blockers, beta-blockers, cyclosporine, and oral contraceptives.
Kis Estella   +2 more
doaj   +1 more source

12-Tungstophosphoric acid–1,1′-methylenebis(imidazolidine-2,4-dione)–imidazolidine-2,4-dione–water (2/1/4/21.5)

open access: yesActa Crystallographica Section E, 2010
In the asymmetric unit of the title organic–inorganic hybrid material, 2{H3[PW12O40]}·4C3H4N2O2·C7H8N4O4·21.5H2O, there are four crystallographically independent hydantoin molecules, one dimerized hydantoin molecule ...
Mohammad Hasan Alizadeh   +1 more
doaj   +1 more source

Sequential Ugi reaction/base-induced ring closing/IAAC protocol toward triazolobenzodiazepine-fused diketopiperazines and hydantoins

open access: yesBeilstein Journal of Organic Chemistry, 2018
A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary ...
Robby Vroemans   +7 more
doaj   +1 more source

5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione

open access: yesActa Crystallographica Section E, 2008
In the title compound, C10H9FN2O2, the dihedral angle between the hydantoin unit and the benzene ring is 65.55 (5)°. The atoms in the hydantoin ring are coplanar, with a mean deviation of 0.015 Å and a maximum deviation of 0.075 ...
Shahid Hameed   +4 more
doaj   +1 more source

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